TLK1 产品
(Tousled-Like Kinase 1 (TLK1))
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The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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Featured TLK1 Categories
Recommended TLK1 抗体
Product
Reactivity
Application
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN564253
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7270859
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN2855507
Quantity
100 μL
Datasheet
Datasheet
Recommended TLK1 蛋白
Product
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Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322843
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317054
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509177
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TLK1 Products
: "DNA damage response and repair data with pharmacological modulators of Tousled." in: Data in brief, Vol. 7, pp. 1073-7, (2016) (PubMed).: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." in: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).
: "Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis." in: Cancer letters, Vol. 296, Issue 1, pp. 27-34, (2010) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1." in: Oncogene, Vol. 22, Issue 38, pp. 5927-37, (2003) (PubMed).
: "Phosphorylation of SNAP-23 by the novel kinase SNAK regulates t-SNARE complex assembly." in: Molecular biology of the cell, Vol. 10, Issue 12, pp. 4033-41, (2000) (PubMed).
Synonyms and alternative names related to TLK1
tousled like kinase 1 (TLK1), tousled-like kinase 1 (Tlk1), tousled-like kinase 1b (tlk1b), tousled like kinase 1 like (TLK1L), tousled-like kinase 1 (TLK1), serine/threonine-protein kinase TOUSLED (LOC542181), tousled-like kinase 1a (tlk1a), tousled like kinase 1 (tlk1), Serine/threonine-protein kinase tousled-like 1 (tlk-1), tousled like kinase 1 (Tlk1), 4930545J15Rik, DKFZp459L163, fb76h12, fe11e12, PKU-beta, si:dkey-88m1.1, si:dkey-251e16.4, tlk1, TLK1, wu:fb76h12, wu:fe11e12Protein level used designations for TLK1
- SNARE protein kinase SNAK
- serine threonine protein kinase
- serine/threonine-protein kinase tousled-like 1
- pKU-beta protein kinase
- serine/threonine-protein kinase tousled-like 1-B
- tousled-like kinase 1
- tousled-like kinase 1-B
- LOW QUALITY PROTEIN: serine/threonine-protein kinase tousled-like 1
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