电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Titin 蛋白

(Titin (TTN))
This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma. [provided by RefSeq, Feb 2012].
Titin Protein (TTN) (AA 14257-14543) (His tag) Titin Protein (TTN) (AA 14257-14543) (His tag) Titin Protein (TTN) (AA 14257-14543) (His tag) (ABIN7125403)

TTN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

Titin Protein (TTN) (AA 1-305) (GST tag) Titin Protein (TTN) (AA 1-305) (GST tag) Titin Protein (TTN) (AA 1-305) (GST tag) (ABIN1324073)

TTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Titin Protein (TTN) (AA 1-110) (GST tag) Titin Protein (TTN) (AA 1-110) (GST tag) Titin Protein (TTN) (AA 1-110) (GST tag) (ABIN1324075)

TTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Titin 蛋白 by Origin

Find Titin 蛋白 for a variety of species such as anti-Human Titin, anti-Mouse Titin. The species listed below are among those available. Click on a link to go to the corresponding products.

Titin 蛋白 by Source

Here you will find Titin 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Titin 蛋白 by 蛋白类型

Here you can find Titin 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Titin 蛋白 by 应用范围

Find Titin 蛋白 validated for a specific application such as WB, ELISA, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Titin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125403
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324073
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324075
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324077
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423204
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394549
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5712956
Quantity 100 μg
Datasheet Datasheet

Aliases for Titin 蛋白

titin (TTN) 蛋白
titin (Ttn) 蛋白
titin (titin) 蛋白
titin (TTNLOC100620261) 蛋白
1100001C23Rik 蛋白
2310036G12Rik 蛋白
2310057K23Rik 蛋白
2310074I15Rik 蛋白
AF006999 蛋白
AV006427 蛋白
CMD1G 蛋白
CMH9 蛋白
CMPD4 蛋白
D330041I19Rik 蛋白
D830007G01Rik 蛋白
EOMFC 蛋白
HMERF 蛋白
L56 蛋白
LGMD2J 蛋白
mdm 蛋白
MYLK5 蛋白
shru 蛋白
TMD 蛋白
UNC-22 蛋白
You are here:
客服