TINF2 产品
(TERF1 Interacting Nuclear Factor 2 (TIN2))
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This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin\; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010].
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TINF2 抗体
High quality antibodies with extensive validation data.
TINF2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TINF2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
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Latest Publications for our TINF2 Products
: "The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005410, (2015) (PubMed).: "Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus." in: Oncogene, Vol. 32, Issue 49, pp. 5522-30, (2013) (PubMed).
: "DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations." in: Frontiers in genetics, Vol. 4, pp. 129, (2013) (PubMed).
: "Characterization of the DNA binding specificity of Shelterin complexes." in: Nucleic acids research, Vol. 39, Issue 21, pp. 9206-23, (2011) (PubMed).
: "The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress." in: Leukemia, Vol. 25, Issue 6, pp. 1017-25, (2011) (PubMed).
: "Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions." in: Nature structural & molecular biology, Vol. 16, Issue 12, pp. 1244-51, (2009) (PubMed).
: "Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference." in: Oncogene, Vol. 26, Issue 32, pp. 4635-47, (2007) (PubMed).
: "Human fetal ovarian culture permits meiotic progression and chromosome pairing process." in: Human reproduction (Oxford, England), Vol. 21, Issue 6, pp. 1359-67, (2006) (PubMed).
: "Chromosome 18 pairing behavior in human trisomic oocytes. Presence of an extra chromosome extends bouquet stage." in: Reproduction (Cambridge, England), Vol. 129, Issue 5, pp. 565-75, (2005) (PubMed).
: "Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes." in: Chromosoma, Vol. 113, Issue 1, pp. 22-33, (2004) (PubMed).
Synonyms and alternative names related to TINF2
TERF1 interacting nuclear factor 2 (TINF2), Terf1 (TRF1)-interacting nuclear factor 2 (Tinf2), AW552114, D14Wsu146e, DKCA3, TIN2, Tin2Protein level used designations for TINF2
- TERF1-interacting nuclear factor 2
- TRF1-interacting nuclear protein 2
- TRF1-interacting nuclear factor 2
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