TIM8 蛋白
(Mitochondrial import inner membrane translocase subunit tim-8 (TIM8))
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane (By similarity). Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane (By similarity). Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity). The ddp-1/tim-8-tim-13 complex mediates the import of some proteins while the predominant tim-9/tin-9.1-tim-10/tin-10 70 kDa complex mediates the import of much more proteins (PubMed:15485840). {ECO:0000250|UniProtKB:Q17754, ECO:0000269|PubMed:15485840}.
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Synonyms and alternative names related to TIM8
Mitochondrial import inner membrane translocase subunit Tim8 (ddp-1)
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