Thyroperoxidase 抗体
(Thyroid Peroxidase (TPO))
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].
recommended
recommended
recommended
TPO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
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Thyroperoxidase 抗体 by 适用
Find Thyroperoxidase 抗体 for a variety of species such as anti-Human Thyroperoxidase, anti-Rat Thyroperoxidase, anti-Mouse Thyroperoxidase. The species listed below are among those available. Click on a link to go to the corresponding products.
Thyroperoxidase 抗体 by 抗体来源
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Thyroperoxidase 抗体 by 克隆形成能力
Find available monoclonal or polyclonal Thyroperoxidase 抗体. Click on a link to go to the corresponding products.
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Cat. No.
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Cat. No.
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Cat. No.
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Validations
Cat. No.
ABIN1700415
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Datasheet
Datasheet
Reactivity
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WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1696791
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Quantity
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Datasheet
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Latest Publications for our Thyroperoxidase 抗体
: "A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2019) (PubMed).: "Long Non-coding Antisense RNA TNRC6C-AS1 Is Activated in Papillary Thyroid Cancer and Promotes Cancer Progression by Suppressing TNRC6C Expression." in: Frontiers in endocrinology, Vol. 9, pp. 360, (2018) (PubMed).
: "Thyroid-Related Protein Expression in the Human Thymus." in: International journal of endocrinology, Vol. 2017, pp. 8159892, (2017) (PubMed).
: "Antibodies to thyroid peroxidase arise spontaneously with age in NOD.H-2h4 mice and appear after thyroglobulin antibodies." in: Endocrinology, Vol. 151, Issue 9, pp. 4583-93, (2010) (PubMed).
: "Adenovirus-mediated transfer of thyroid transcription factor-1 induces radioiodide organification and retention in thyroid cancer cells." in: Endocrinology, Vol. 145, Issue 11, pp. 5397-405, (2004) (PubMed).
: "Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and ..." in: Endocrinology, Vol. 145, Issue 6, pp. 2865-75, (2004) (PubMed).
: "Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases." in: The Journal of biological chemistry, Vol. 278, Issue 11, pp. 9560-9, (2003) (PubMed).
Aliases for Thyroperoxidase 抗体
thyroid peroxidase (TPO) 抗体thyroid peroxidase (Tpo) 抗体
thyroid peroxidase (tpo) 抗体
thyroid peroxidase (LOC100547103) 抗体
LOC100218312 抗体
MSA 抗体
msa 抗体
TDH2A 抗体
TPO 抗体
TPX 抗体
tpx 抗体
xtpo 抗体
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