Thiamine Biosynthesis2 蛋白
(Thiamine Biosynthesis2 (THI2))
Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
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Thiamine Biosynthesis2 蛋白
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Synonyms and alternative names related to Thiamine Biosynthesis2
thiamine biosynthesis 2 (thi2), thi1-2Protein level used designations for Thiamine Biosynthesis2
- PCO074324
- PCO074324(276)
- PCO074324_ov
- Sed2
- bladekiller1
- blk1
- iger2a(thi)
- pcPOG1
- senescence-diminished2
- thi*-U17351
- thiamine biosynthetic enzyme
- thiamine thiazole synthase 2, chloroplastic
- thiazole biosynthetic enzyme 1-2, chloroplastic
- thiazole biosynthetic enzyme 2
- uiu1a(pog)
- uiu2
- uiu2(pog1a)
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