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TGF-beta 产品

(TGF-beta (TGFb))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured TGF-beta Categories

TGF-beta 抗体

High quality antibodies with extensive validation data.

TGF-beta ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TGF-beta 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TGF-beta 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rabbit, Rat, Sheep
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN707021
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mammalian, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (1)
Cat. No. ABIN2476753
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
Application ELISA, Func, D, ELISA (Capture)
Validations
  • (1)
Cat. No. ABIN6940723
Quantity 100 μg
Datasheet Datasheet

Recommended TGF-beta ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Monkey
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1059453
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1059454
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Competition ELISA
Validations
Cat. No. ABIN1059452
Quantity 96 tests
Datasheet Datasheet

Recommended TGF-beta 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Hi-5 Cells
Validations
Cat. No. ABIN2469123
Quantity 0.002 mg
Datasheet Datasheet

Latest Publications for our TGF-beta Products

Baumeier, Escher, Aleshcheva, Pietsch, Schultheiss: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." in: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).

Playford, Cattell, Marchbank: "Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials." in: PLoS ONE, Vol. 15, Issue 6, pp. e0234719, (2020) (PubMed).

Sunil Gowda, Rajasowmiya, Vadivel, Banu Devi, Celestin Jerald, Marimuthu, Devipriya: "Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 52, pp. 170-177, (2018) (PubMed).

Xia, Ren, Zhu, Yu, Zhang, Sun, Zhao, Chen: "Downregulation of miR-145 in venous malformations: Its association with disorganized vessels and sclerotherapy." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 100, pp. 126-131, (2017) (PubMed).

Chen, Ren, Zhang, Sun, Wang, Li, Zhang, Zhao: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." in: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).

Polichnowski, Lan, Geng, Griffin, Venkatachalam, Bidani: "Severe renal mass reduction impairs recovery and promotes fibrosis after AKI." in: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 7, pp. 1496-507, (2014) (PubMed).

Bob, Gluhovschi, Herman, Petrica, Bozdog, Gluhovschi, Velciov, Gadalean, Timar, Potencz, Dema, Schiller: "Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis." in: Renal failure, Vol. 36, Issue 8, pp. 1208-14, (2014) (PubMed).

Moore, Sawyer, Charokopos, Skokos, Kyriakides: "Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NF?B activation in the foreign body response." in: Acta biomaterialia, Vol. 11, pp. 37-47, (2014) (PubMed).

Geng, Lan, Singha, Gilchrist, Weinreb, Violette, Weinberg, Saikumar, Venkatachalam: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).

Mortarini, Vegetti, Molla, Arienti, Ravagnani, Maurichi, Patuzzo, Santinami, Anichini: "Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 12, pp. 4085-94, (2009) (PubMed).

Synonyms and alternative names related to TGF-beta

transforming growth factor beta 1 (TGFB1), transforming growth factor beta-1 (TGFB1), transforming growth factor beta 1 (Tgfb1), transforming growth factor, beta 1 (Tgfb1), CED, DPD1, LAP, TGF-beta, TGF-BETA-1, TGF-beta1, TGFB, Tgfb, Tgfb-1, TGFbeta, TGFbeta1

Protein level used designations for TGF-beta

  • TGF-beta 1 protein
  • TGF-beta-1
  • latency-associated peptide
  • transforming growth factor beta-1
  • transforming growth factor, beta 1 (Camurati-Engelmann disease)
  • transforming growth factor-beta 1
  • transforming growth factor beta 1
  • transforming growth factor-beta
  • transforming growth factor beta1
  • transforming growth factor-beta-1
  • TGF-beta 1
  • regulatory protein
  • transforming growth factor, beta-1
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