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TFEB 蛋白

(Transcription Factor EB (TFEB))

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.

recommended

TFEB Protein (AA 43-200) (His-IF2DI Tag) (ABIN7125448)

TFEB 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB

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recommended

TFEB Protein (AA 1-476) (GST tag) (ABIN1786750)

TFEB 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

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recommended

TFEB Protein (His tag) (ABIN2733467)

TFEB 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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TFEB 蛋白 by Origin

Find TFEB 蛋白 for a variety of species such as anti-Human TFEB, anti-Mouse TFEB. The species listed below are among those available. Click on a link to go to the corresponding products.

TFEB 蛋白 by Source

Here you will find TFEB 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

TFEB 蛋白 by 蛋白类型

Here you can find TFEB 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

TFEB 蛋白 by 应用范围

Find TFEB 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular TFEB 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

TFEB Protein (AA 43-200) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125448

Quantity 50 μg

Datasheet Datasheet

TFEB Protein (AA 1-476) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1786750

Quantity 10 μg

Datasheet Datasheet

TFEB Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2733467

Quantity 50 μg

Datasheet Datasheet

TFEB Protein (AA 1-476) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3095870

Quantity 1 mg

Datasheet Datasheet

TFEB Protein (AA 1-475) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3137468

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our TFEB 蛋白

Song, Sun, Peluso, Zeng, Yu, Lu, Xu, Wang, Liu, Huang, Chen, Durairajan, Zhang, Zhou, Zhang, Lu, Ballabio, Medina, Guo, Li: "A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition." in: Autophagy, Vol. 12, Issue 8, pp. 1372-89, (2016) (PubMed).

Aliases for TFEB 蛋白

transcription factor EB (TFEB) 蛋白
transcription factor EB (tfeb) 蛋白
transcription factor EB (Tfeb) 蛋白
alphatfeb 蛋白
ALPHATFEB 蛋白
BHLHE35 蛋白
bHLHe35 蛋白
MGC145796 蛋白
tcfeb 蛋白
TCFEB 蛋白
Tcfeb 蛋白
TFEB 蛋白

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TFEB 蛋白 by Origin

TFEB 蛋白 by Source

TFEB 蛋白 by 蛋白类型

TFEB 蛋白 by 应用范围

Popular TFEB 蛋白

Latest Publications for our TFEB 蛋白

Aliases for TFEB 蛋白

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