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TFAM 产品

(Transcription Factor A, Mitochondrial (TFAM))

Categories

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Featured TFAM Categories

TFAM 抗体

High quality antibodies with extensive validation data.

TFAM ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TFAM 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TFAM 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit
Application WB
Validations
  • (10)
  • (6)
Cat. No. ABIN2777277
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7438793
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ChIP
Validations
  • (6)
Cat. No. ABIN6149024
Quantity 100 μL
Datasheet Datasheet

Recommended TFAM ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960059
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960058
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4973162
Quantity 96 tests
Datasheet Datasheet

Recommended TFAM 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125440
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408864
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1989795
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our TFAM Products

Yamanishi, Doe, Mukai, Ikubo, Hashimoto, Uwa, Sumida, El-Darawish, Gamachi, Li, Kuwahara-Otani, Maeda, Watanabe, Hayakawa, Yamanishi, Matsuyama, Yagi, Okamura, Matsunaga: "Interleukin-18-deficient mice develop hippocampal abnormalities related to possible depressive-like behaviors." in: Neuroscience, Vol. 408, pp. 147-160, (2019) (PubMed).

Manczak, Kandimalla, Yin, Reddy: "Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity." in: Human molecular genetics, Vol. 28, Issue 2, pp. 177-199, (2019) (PubMed).

Kamel, Abdelkader, Abd El-Rahman, Emara, Zaki, Khattab: "Stimulation of ACE2/ANG(1-7)/Mas Axis by Diminazene Ameliorates Alzheimer's Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway." in: Molecular neurobiology, Vol. 55, Issue 10, pp. 8188-8202, (2018) (PubMed).

Widdrington, Gomez-Duran, Pyle, Ruchaud-Sparagano, Scott, Baudouin, Rostron, Lovat, Chinnery, Simpson: "Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses." in: Frontiers in immunology, Vol. 9, pp. 2217, (2018) (PubMed).

Huang, Wang, Yang, Chiou, Tan, Lin, Huang: "Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 39, pp. 75-84, (2018) (PubMed).

Dlasková, Engstová, Špaček, Kahancová, Pavluch, Smolková, Špačková, Bartoš, Hlavatá, Ježek: "3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution." in: Biochimica et biophysica acta. Bioenergetics, Vol. 1859, Issue 9, pp. 829-844, (2018) (PubMed).

Yang, Li, Zhu, Cao, Kroemer, Zeh, Tang, Kang: "TFAM is a novel mediator of immunogenic cancer cell death." in: Oncoimmunology, Vol. 7, Issue 6, pp. e1431086, (2018) (PubMed).

Yan, Liu, Guan, Guo: "Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." in: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).

Wu, Zhao, Xiao, Peng, Chen, He: "Roles of mitochondrial transcription factor A and microRNA‑590‑3p in the development of colon cancer." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5475-5480, (2017) (PubMed).

Mastrocola, Penna, Tullio, Femminò, Nigro, Chiazza, Serpe, Collotta, Alloatti, Cocco, Bertinaria, Pagliaro, Aragno, Collino: "Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5271251, (2017) (PubMed).

Synonyms and alternative names related to TFAM

transcription factor A, mitochondrial (TFAM), transcription factor A, mitochondrial L homeolog (tfam.L), transcription factor A, mitochondrial (tfam), transcription factor A, mitochondrial (Tfam), AI661103, Hmgts, MGC153358, mttf1, MTTF1, mttfa, MTTFA, mtTFA, Mttfa, mttfa-A, tcf6, TCF6, tcf6l1, TCF6L1, tcf6l2, TCF6L2, tcf6l3, TCF6L3, tsHMG, xl-mtTFA, zgc:153358

Protein level used designations for TFAM

  • transcription factor A, mitochondrial
  • HMG box mitochondrial transcription factor
  • mitochondrial transcription factor 1
  • mitochondrial transcription factor A
  • transcription factor 6
  • transcription factor 6-like 1
  • transcription factor 6-like 2 (mitochondrial transcription factor)
  • transcription factor 6-like 3
  • mtTFA
  • transcription factor 6-like 2
  • TS-HMG
  • testis-specific HMG-box protein m-tsHMG
  • testis-specific high mobility group protein
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