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TET1 蛋白

(Tet Methylcytosine Dioxygenase 1 (TET1))

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5- hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification.

recommended

TET1 Protein (AA 2038-2136) (GST tag) (ABIN1322493)

TET1 宿主: 人宿主: 小麦胚 Recombinant WB, AP, AA, ELISA

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recommended

TET1 Protein (GST tag) (ABIN6700690)

TET1 宿主: 人宿主: Baculovirus infected Insect Cells, Insect cells (Sf9) WB

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TET1 蛋白 by Origin

Find TET1 蛋白 for a variety of species such as anti-Human TET1. The species listed below are among those available. Click on a link to go to the corresponding products.

TET1 蛋白 by Source

Here you will find TET1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

TET1 蛋白 by 蛋白类型

Here you can find TET1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

TET1 蛋白 by 应用范围

Find TET1 蛋白 validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular TET1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

TET1 Protein (AA 2038-2136) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1322493

Quantity 10 μg

Datasheet Datasheet

TET1 Protein (GST tag)

Reactivity Human

Source Baculovirus infected Insect Cells, Insect cells (Sf9)

Validations

Cat. No. ABIN6700690

Quantity 50 μg

Datasheet Datasheet

Aliases for TET1 蛋白

tet methylcytosine dioxygenase 1 (TET1) 蛋白
tet methylcytosine dioxygenase 1 (Tet1) 蛋白
solute carrier family 25 member 16 (SLC25A16) 蛋白
2510010B09Rik 蛋白
AA517754 蛋白
bA119F7.1 蛋白
BB001228 蛋白
CXXC6 蛋白
Cxxc6 蛋白
D10Ertd17e 蛋白
LCX 蛋白
mKIAA1676 蛋白

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TET1 蛋白 by Origin

TET1 蛋白 by Source

TET1 蛋白 by 蛋白类型

TET1 蛋白 by 应用范围

Popular TET1 蛋白

Aliases for TET1 蛋白

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