TET1 抗体
(Tet Methylcytosine Dioxygenase 1 (TET1))
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5- hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification.
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TET1 抗体 by Grade
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TET1 抗体 by 适用
Find TET1 抗体 for a variety of species such as anti-Human TET1, anti-Mouse TET1, anti-Rat TET1. The species listed below are among those available. Click on a link to go to the corresponding products.
TET1 抗体 by 应用范围
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TET1 抗体 by 抗体来源
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TET1 抗体 by 抗原表位
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TET1 抗体 by 克隆形成能力
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TET1 抗体 by 克隆
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TET1 抗体 by 标记
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Popular TET1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN1327194
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7159633
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN6244141
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ChIP, ChIP-seq
Validations
- (1)
Cat. No.
ABIN6972860
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC
Validations
- (1)
Cat. No.
ABIN7270777
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3029115
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7159634
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7159636
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC (p)
Validations
Cat. No.
ABIN6991985
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IP
Validations
Cat. No.
ABIN6758522
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
Cat. No.
ABIN2742554
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN2612528
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IHC (p)
Validations
Cat. No.
ABIN2612530
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
Cat. No.
ABIN7464383
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our TET1 抗体
: "Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs." in: Stem cells international, Vol. 2018, pp. 6013728, (2018) (PubMed).: "TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing." in: The EMBO journal, Vol. 35, Issue 3, pp. 335-55, (2016) (PubMed).
: "Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate." in: The Journal of biological chemistry, Vol. 291, Issue 13, pp. 6754-71, (2016) (PubMed).
: "Promoter demethylation of nuclear factor-erythroid 2-related factor 2 gene in drug-resistant colon cancer cells." in: Oncology letters, Vol. 10, Issue 3, pp. 1287-1292, (2015) (PubMed).
: "Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the O-linked N-acetylglucosamine transferase (OGT)." in: The Journal of biological chemistry, Vol. 290, Issue 8, pp. 4801-12, (2015) (PubMed).
: "TET1-mediated different transcriptional regulation in prostate cancer." in: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 203-11, (2015) (PubMed).
Aliases for TET1 抗体
tet methylcytosine dioxygenase 1 (TET1) 抗体tet methylcytosine dioxygenase 1 (Tet1) 抗体
solute carrier family 25 member 16 (SLC25A16) 抗体
2510010B09Rik 抗体
AA517754 抗体
bA119F7.1 抗体
BB001228 抗体
CXXC6 抗体
Cxxc6 抗体
D10Ertd17e 抗体
LCX 抗体
mKIAA1676 抗体
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