TERT 抗体
(Telomerase Reverse Transcriptase (TERT))
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified\; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
TERT 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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TERT 抗体 by 适用
Find TERT 抗体 for a variety of species such as anti-Human TERT, anti-Mouse TERT, anti-Rat TERT. The species listed below are among those available. Click on a link to go to the corresponding products.
TERT 抗体 by 抗体来源
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TERT 抗体 by 克隆形成能力
Find available monoclonal or polyclonal TERT 抗体. Click on a link to go to the corresponding products.
TERT 抗体 by 克隆
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, ELISA, IHC, IF, IP, FM
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, ELISA, IHC, IF, IP, FM
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Datasheet
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Datasheet
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Datasheet
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Latest Publications for our TERT 抗体
: "Evaluation of Some Prognostic Biomarkers in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma." in: Iranian journal of medical sciences, Vol. 49, Issue 3, pp. 156-166, (2024) (PubMed).: "Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus." in: iScience, Vol. 25, Issue 6, pp. 104383, (2022) (PubMed).
: "The clinical and functional effects of TERT variants in myelodysplastic syndrome." in: Blood, Vol. 138, Issue 10, pp. 898-911, (2021) (PubMed).
: "Telomerase therapy attenuates cardiotoxic effects of doxorubicin." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 29, Issue 4, pp. 1395-1410, (2021) (PubMed).
: "Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner." in: The EMBO journal, Vol. 40, Issue 9, pp. e106048, (2021) (PubMed).
: "HIF-1α and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles." in: International journal of molecular sciences, Vol. 22, Issue 7, (2021) (PubMed).
: "Extracellular vesicles from rat-bone-marrow mesenchymal stromal/stem cells improve tendon repair in rat Achilles tendon injury model in dose-dependent manner: A pilot study." in: PloS one, Vol. 15, Issue 3, pp. e0229914, (2020) (PubMed).
: "Telomerase promotes formation of a telomere protective complex in cancer cells." in: Science advances, Vol. 5, Issue 10, pp. eaav4409, (2020) (PubMed).
: "Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells." in: The Journal of biological chemistry, Vol. 294, Issue 27, pp. 10564-10578, (2020) (PubMed).
: "Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With ..." in: Frontiers in veterinary science, Vol. 7, pp. 148, (2020) (PubMed).
Aliases for TERT 抗体
telomerase reverse transcriptase (TERT) 抗体Telomerase Reverse Transcriptase (trt-1) 抗体
telomerase reverse transcriptase (Tert) 抗体
telomerase reverse transcriptase (tert) 抗体
Tertp (TERT) 抗体
telomerase reverse transcriptase (CMU_003490) 抗体
telomerase reverse transcriptase (VDBG_04487) 抗体
Telomerase catalytic subunit (GL50803_16225) 抗体
telomerase reverse transcriptase L homeolog (tert.L) 抗体
ATTERT 抗体
chTERT 抗体
CMM9 抗体
DKCA2 抗体
DKCB4 抗体
EST2 抗体
est2 抗体
F5E19.190 抗体
F5E19_190 抗体
hEST2 抗体
hTRT 抗体
PFBMFT1 抗体
TCS1 抗体
tcs1 抗体
telomerase 抗体
telomerase reverse transcriptase 抗体
Tert 抗体
tert 抗体
tert-A 抗体
TP2 抗体
tp2 抗体
TR 抗体
TRT 抗体
trt 抗体
xTERT 抗体
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