TEK 产品
(TEK Tyrosine Kinase, Endothelial (TEK))
Categories
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations\; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008].
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Featured TEK Categories
TEK 抗体
High quality antibodies with extensive validation data.
TEK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TEK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TEK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN1327048
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193241
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN3029103
Quantity
0.4 mL
Datasheet
Datasheet
Recommended TEK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6730884
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959878
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959877
Quantity
96 tests
Datasheet
Datasheet
Recommended TEK 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN6992355
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322461
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7320054
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TEK Products
: "Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis." in: eLife, Vol. 9, (2020) (PubMed).: "PADI4 stimulates esophageal squamous cell carcinoma tumor growth and up-regulates CA9 expression." in: Molecular carcinogenesis, Vol. 58, Issue 1, pp. 66-75, (2019) (PubMed).
: "A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche." in: Haematologica, (2019) (PubMed).
: "Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure." in: Human reproduction (Oxford, England), Vol. 33, Issue 5, pp. 832-843, (2018) (PubMed).
: "MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. ..." in: Gut, Vol. 67, Issue 2, pp. 333-347, (2018) (PubMed).
: "Tie2 protects the vasculature against thrombus formation in systemic inflammation." in: The Journal of clinical investigation, Vol. 128, Issue 4, pp. 1471-1484, (2018) (PubMed).
: "Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF." in: Oncotarget, Vol. 9, Issue 1, pp. 726-742, (2018) (PubMed).
: "Pulmonary pericytes regulate lung morphogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).
: "Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs." in: Molecular therapy. Nucleic acids, Vol. 10, pp. 349-360, (2018) (PubMed).
: "Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock." in: Anesthesiology, Vol. 128, Issue 2, pp. 361-374, (2018) (PubMed).
Synonyms and alternative names related to TEK
TEK receptor tyrosine kinase (TEK), angiopoietin-1 receptor (LOC100408334), TEK receptor tyrosine kinase (tek), TEK receptor tyrosine kinase (Tek), TEK tyrosine kinase, endothelial (tek), AA517024, Cd202b, CD202B, DKFZp469E064, Hyk, TEK, tie-2, TIE-2, Tie-2, Tie2, TIE2, tie2, VMCM, VMCM1Protein level used designations for TEK
- growth factor receptor Tie2/Tek
- TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)
- Angiopoietin-1 receptor
- TEK tyrosine kinase, endothelial
- angiopoietin-1 receptor-like
- STK1
- angiopoietin-1 receptor
- endothelial tyrosine kinase
- mTIE2
- p140 TEK
- tunica interna endothelial cell kinase
- tyrosine kinase with Ig and EGF homology domains-2
- tyrosine-protein kinase receptor TEK
- tyrosine-protein kinase receptor TIE-2
- hTIE2
- soluble TIE2 variant 1
- soluble TIE2 variant 2
- protein-tyrosine kinase Tie2
- endothelial-specific receptor tyrosine kinase
- tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2
- endothelium-specific receptor tyrosine kinase 2
- tyrosine-protein kinase receptor Tie-2
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