TEAD2 产品
(TEA Domain Family Member 2 (TEAD2))
Categories
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction (By similarity). Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
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Featured TEAD2 Categories
Recommended TEAD2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN570968
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ICC, DB
Validations
- (2)
Cat. No.
ABIN931123
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7303454
Quantity
100 μL
Datasheet
Datasheet
Recommended TEAD2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6207953
Quantity
96 tests
Datasheet
Datasheet
Recommended TEAD2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322442
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322441
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095878
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TEAD2 Products
: "Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology." in: Human molecular genetics, (2016) (PubMed).: "The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25400-13, (2013) (PubMed).
: "Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival." in: Molecular and cellular biology, Vol. 28, Issue 10, pp. 3177-89, (2008) (PubMed).
Synonyms and alternative names related to TEAD2
TEA domain transcription factor 2 (TEAD2), TEA domain family member 2 (Tead2), TEA domain transcription factor 2 (Tead2), Etdf, ETF, TEAD-2, TEAD2, TEF-4, TEF4Protein level used designations for TEAD2
- TEA domain family member 2
- transcriptional enhancer factor TEF-4-like
- transcriptional enhancer factor TEF-4
- ETEF-1
- embryonic TEA domain-containing factor
- Embryonic TEA domain containing factor
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