TCF7L2 产品
(Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
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This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010].
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Featured TCF7L2 Categories
TCF7L2 抗体
High quality antibodies with extensive validation data.
TCF7L2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TCF7L2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TCF7L2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (cc), IHC (p), IHC, FACS
Validations
- (1)
- (2)
- (1)
Cat. No.
ABIN6945139
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN520778
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (1)
- (4)
Cat. No.
ABIN563117
Quantity
100 μg
Datasheet
Datasheet
Recommended TCF7L2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970769
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960753
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6223776
Quantity
96 tests
Datasheet
Datasheet
Recommended TCF7L2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1785451
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322377
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095869
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TCF7L2 Products
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991): "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).
: "Targeted interference of SIN3A-TGIF1 function by SID decoy treatment inhibits Wnt signaling and invasion in triple negative breast cancer cells." in: Oncotarget, Vol. 8, Issue 51, pp. 88421-88436, (2017) (PubMed).
: "Macrophage TCF-4 co-activates p65 to potentiate chronic inflammation and insulin resistance in mice." in: Clinical science (London, England : 1979), Vol. 130, Issue 14, pp. 1257-68, (2016) (PubMed).
: "TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells." in: Diabetes, Vol. 58, Issue 4, pp. 894-905, (2009) (PubMed).
: "Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS." in: Genes & development, Vol. 23, Issue 13, pp. 1571-85, (2009) (PubMed).
: "Dazap2 modulates transcription driven by the Wnt effector TCF-4." in: Nucleic acids research, Vol. 37, Issue 9, pp. 3007-20, (2009) (PubMed).
: "Regulation of Wnt signaling by the nuclear pore complex." in: Gastroenterology, Vol. 134, Issue 7, pp. 1961-71, 1971.e1-4, (2008) (PubMed).
: "A Ras-induced conformational switch in the Ras activator Son of sevenless." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 45, pp. 16692-7, (2006) (PubMed).
: "Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline." in: Neuron, Vol. 52, Issue 4, pp. 595-607, (2006) (PubMed).
Synonyms and alternative names related to TCF7L2
transcription factor 7 like 2 (TCF7L2), transcription factor 7-like 2 (LOC100545943), transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2), transcription factor 7 like 2 (tcf7l2), transcription factor 7 like 2 L homeolog (tcf7l2.L), transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcription factor 7 like 2 (Tcf7l2), mTcf-4B, mTcf-4E, Tcf-4, TCF-4, Tcf4, tcf4, TCF4, TCF4B, TCF4E, tcf4e, TCFL2, XTCF-4Protein level used designations for TCF7L2
- transcription factor 7-like 2 (T-cell specific, HMG-box)
- HMG box transcription factor 4
- T-cell factor 4
- T-cell-specific transcription factor 4
- mTCF-4
- transcription factor 7-like 2
- transcription factor 7-like 2, T-cell specific, HMG-box
- transcription factor tcf4
- T-cell factor XTCF-4A
- transcription factor Tcf4
- T-cell factor-4 variant A
- T-cell factor-4 variant B
- T-cell factor-4 variant C
- T-cell factor-4 variant D
- T-cell factor-4 variant E
- T-cell factor-4 variant F
- T-cell factor-4 variant G
- T-cell factor-4 variant H
- T-cell factor-4 variant I
- T-cell factor-4 variant J
- T-cell factor-4 variant K
- T-cell factor-4 variant L
- T-cell factor-4 variant M
- T-cell factor-4 variant X2
- hTCF-4
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