TCAP 产品
(Titin-Cap (Telethonin) (TCAP))
Categories
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008].
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Featured TCAP Categories
Recommended TCAP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN522010
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7171700
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7246484
Quantity
200 μL
Datasheet
Datasheet
Recommended TCAP 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322319
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322316
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3074021
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TCAP Products
: "A pilot study of muscle plasma protein changes after exercise." in: Muscle & nerve, Vol. 49, Issue 2, pp. 261-6, (2014) (PubMed).: "Early and selective disappearance of telethonin protein from the sarcomere in neurogenic atrophy." in: Journal of muscle research and cell motility, Vol. 22, Issue 3, pp. 259-64, (2001) (PubMed).
: "Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin." in: Nature genetics, Vol. 24, Issue 2, pp. 163-6, (2000) (PubMed).
: "The novel sarcomeric protein telethonin exhibits developmental and functional regulation." in: Biochemical and biophysical research communications, Vol. 257, Issue 3, pp. 699-703, (1999) (PubMed).
: "Telethonin, a novel sarcomeric protein of heart and skeletal muscle." in: FEBS letters, Vol. 415, Issue 2, pp. 163-8, (1997) (PubMed).
Synonyms and alternative names related to TCAP
titin-cap (TCAP), titin-cap (telethonin) (tcap), titin-cap (tcap), titin-cap S homeolog (tcap.S), titin-cap (Tcap), AI503981, AJ223855, CMD1N, LGMD2G, T-cap, TCAP, TELE, telethoninProtein level used designations for TCAP
- titin-cap (telethonin)
- 19 kDa sarcomeric protein
- limb girdle muscular dystrophy 2G (autosomal recessive)
- telethonin
- titin cap protein
- titin-cap protein
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