电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TBP 抗体

(TATA Box Binding Protein (TBP))
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010].
TBP 抗体  (AA 1-144) TBP 抗体  (AA 1-144) TBP 抗体 (AA 1-144) (ABIN7193395)

TBP 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7G11C8 unconjugated

TBP 抗体  (AA 210-239) TBP 抗体  (AA 210-239) TBP 抗体 (AA 210-239) (ABIN3029099)

TBP 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

TBP 抗体 TBP 抗体 TBP 抗体 (ABIN3029100)

TBP 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 830CT4-3-3 unconjugated

TBP 抗体 by Grade

Find TBP 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TBP 抗体 by 适用

Find TBP 抗体 for a variety of species such as anti-Human TBP, anti-Mouse TBP, anti-Rat TBP. The species listed below are among those available. Click on a link to go to the corresponding products.

TBP 抗体 by 应用范围

Find TBP 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

TBP 抗体 by 抗体来源

Find TBP 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TBP 抗体 by 抗原表位

Find TBP 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TBP 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TBP 抗体. Click on a link to go to the corresponding products.

TBP 抗体 by 克隆

Find TBP 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TBP 抗体 by 标记

Find TBP 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TBP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (8)
Cat. No. ABIN7193395
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (6)
Cat. No. ABIN3029099
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (8)
Cat. No. ABIN3029100
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN3029098
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265482
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN987280
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN390631
Quantity 400 μL
Datasheet Datasheet
Reactivity Cynomolgus, Human, Mouse, Rat
Application WB, IHC (p), IF (cc)
Validations
  • (2)
Cat. No. ABIN4914538
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7441898
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7171581
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6257528
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p)
Validations
  • (2)
Cat. No. ABIN7250434
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3023175
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN390630
Quantity 400 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7301360
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TBP 抗体

Basic, Tadele, Elmabsout, Yao, Rahman, Sirsjö, Abdel-Halim: "Exposure to cigarette smoke induces overexpression of von Hippel-Lindau tumor suppressor in mouse skeletal muscle." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 303, Issue 6, pp. L519-27, (2012) (PubMed).

Denissov, van Driel, Voit, Hekkelman, Hulsen, Hernandez, Grummt, Wehrens, Stunnenberg: "Identification of novel functional TBP-binding sites and general factor repertoires." in: The EMBO journal, Vol. 26, Issue 4, pp. 944-54, (2007) (PubMed).

Helmlinger, Hardy, Abou-Sleymane, Eberlin, Bowman, Gansmüller, Picaud, Zoghbi, Trottier, Tora, Devys: "Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction." in: PLoS biology, Vol. 4, Issue 3, pp. e67, (2006) (PubMed).

Raha, Cheng, Green: "HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs." in: PLoS biology, Vol. 3, Issue 2, pp. e44, (2005) (PubMed).

Reid, van Roon-Mom, Wood, Rees, Owen, Faull, Dragunow, Snell: "TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease." in: Brain research. Molecular brain research, Vol. 125, Issue 1-2, pp. 120-8, (2004) (PubMed).

Martianov, Brancorsini, Gansmuller, Parvinen, Davidson, Sassone-Corsi: "Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids." in: Development (Cambridge, England), Vol. 129, Issue 4, pp. 945-55, (2002) (PubMed).

Brou, Chaudhary, Davidson, Lutz, Wu, Egly, Tora, Chambon: "Distinct TFIID complexes mediate the effect of different transcriptional activators." in: The EMBO journal, Vol. 12, Issue 2, pp. 489-99, (1993) (PubMed).

Hoffman, Sinn, Yamamoto, Wang, Roy, Horikoshi, Roeder: "Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)." in: Nature, Vol. 346, Issue 6282, pp. 387-90, (1990) (PubMed).

Peterson, Tanese, Pugh, Tjian: "Functional domains and upstream activation properties of cloned human TATA binding protein." in: Science (New York, N.Y.), Vol. 248, Issue 4963, pp. 1625-30, (1990) (PubMed).

Kao, Lieberman, Schmidt, Zhou, Pei, Berk: "Cloning of a transcriptionally active human TATA binding factor." in: Science (New York, N.Y.), Vol. 248, Issue 4963, pp. 1646-50, (1990) (PubMed).

Aliases for TBP 抗体

TATA-box binding protein (TBP) 抗体
TATA box binding protein (Tbp) 抗体
TATA box binding protein (tbp) 抗体
TATA box binding protein (TBP) 抗体
TATA-box binding protein (tbp) 抗体
TATA binding protein (Tbp) 抗体
TATA-box binding protein L homeolog (tbp.L) 抗体
TATA-box binding protein (Tbp) 抗体
TATA-box-binding protein (Tbp) 抗体
TATA-box binding protein S homeolog (tbp.S) 抗体
CG9874 抗体
Dmel\\CG9874 抗体
dTBP 抗体
dTbp 抗体
dtbp 抗体
dTFIID 抗体
fd20h06 抗体
GTF2D 抗体
Gtf2d 抗体
gtf2d 抗体
GTF2D1 抗体
gtf2d1 抗体
HDL4 抗体
RBP 抗体
SCA17 抗体
sca17 抗体
si:zc101n13.2 抗体
TBP 抗体
tbp 抗体
tbp-a 抗体
tbp-b 抗体
TBP1 抗体
TBP38 抗体
TFIID 抗体
TfIID 抗体
tfiid 抗体
TFIIDtau 抗体
tfiidtau 抗体
wu:fd20h06 抗体
xtbp 抗体
zgc:66213 抗体
You are here:
客服