TBK1 产品
(TANK-Binding Kinase 1 (TBK1))
Categories
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010].
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Featured TBK1 Categories
TBK1 抗体
High quality antibodies with extensive validation data.
TBK1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TBK1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TBK1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN3016268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF
Validations
- (6)
Cat. No.
ABIN7270723
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Monkey, Mouse, Rat
Application
WB
Validations
- (3)
- (4)
Cat. No.
ABIN746363
Quantity
100 μL
Datasheet
Datasheet
Recommended TBK1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN4889796
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970559
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959861
Quantity
96 tests
Datasheet
Datasheet
Recommended TBK1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322250
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322248
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509171
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TBK1 Products
: "Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro." in: Vaccines, Vol. 8, Issue 1, (2020) (PubMed).: "Porcine FcγRIIb mediated PRRSV ADE infection through inhibiting IFN-β by cytoplasmic inhibitory signal transduction." in: International journal of biological macromolecules, Vol. 138, pp. 198-206, (2020) (PubMed).
: "Signalling strength determines proapoptotic functions of STING." in: Nature communications, Vol. 8, Issue 1, pp. 427, (2018) (PubMed).
: "Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells." in: Mediators of inflammation, Vol. 2017, pp. 9891673, (2018) (PubMed).
: "NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3." in: Journal of virology, Vol. 92, Issue 23, (2018) (PubMed).
: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).
: "Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) suppresses STING-mediated DNA sensing pathway through inducing mitochondrial fission." in: Biochemical and biophysical research communications, Vol. 493, Issue 1, pp. 737-743, (2017) (PubMed).
: "Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling." in: European journal of immunology, Vol. 46, Issue 4, pp. 971-80, (2016) (PubMed).
: "Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines." in: Redox biology, Vol. 6, pp. 9-18, (2015) (PubMed).
: "Autophagy facilitates Salmonella replication in HeLa cells." in: mBio, Vol. 5, Issue 2, pp. e00865-14, (2014) (PubMed).
Synonyms and alternative names related to TBK1
TANK binding kinase 1 L homeolog (tbk1.L), TANK binding kinase 1 (TBK1), TANK-binding kinase 1 (tbk1), TANK binding kinase 1 (tbk1), TANK-binding kinase 1 (Tbk1), 1200008B05Rik, AI462036, AW048562, nak, NAK, t2k, T2K, TBK1, wu:fk70c05, zgc:136548Protein level used designations for TBK1
- serine/threonine-protein kinase TBK1
- TANK-binding kinase 1
- NF-kappa-B-activating kinase
- TANK binding kinase 1
- serine/threonine protein kinase TBK1
- serine/threonine-protein kinase TBK1-like
- NF-kB-activating kinase
- T2K
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