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TBCE 产品

(Tubulin Folding Cofactor E (TBCE))

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Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured TBCE Categories

TBCE 抗体

High quality antibodies with extensive validation data.

TBCE ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TBCE 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TBCE 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN520724
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7173754
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN948525
Quantity 100 μL
Datasheet Datasheet

Recommended TBCE ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1164297
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1164298
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1164299
Quantity 96 tests
Datasheet Datasheet

Recommended TBCE 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322246
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733291
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733290
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our TBCE Products

Vennemann, Alessandrini, Wiemann: "Differential Effects of Surface-Functionalized Zirconium Oxide Nanoparticles on Alveolar Macrophages, Rat Lung, and a Mouse Allergy Model." in: Nanomaterials (Basel, Switzerland), Vol. 7, Issue 9, (2017) (PubMed).

Sferra, Baillat, Rizza, Barresi, Flex, Tasca, DAmico, Bellacchio, Ciolfi, Caputo, Cecchetti, Torella, Zanni, Diodato, Piermarini, Niceta, Coppola, Tedeschi, Martinelli, Dionisi-Vici, Nigro et al.: "TBCE Mutations Cause Early-Onset Progressive Encephalopathy with Distal Spinal Muscular Atrophy. ..." in: American journal of human genetics, Vol. 99, Issue 4, pp. 974-983, (2016) (PubMed).

Savard, Brochu, Chevin, Guiraut, Grbic, Sébire: "Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia." in: Journal of neuroinflammation, Vol. 12, pp. 111, (2016) (PubMed).

Bellouze, Schäfer, Buttigieg, Baillat, Rabouille, Haase: "Golgi fragmentation in pmn mice is due to a defective ARF1/TBCE cross-talk that coordinates COPI vesicle formation and tubulin polymerization." in: Human molecular genetics, Vol. 23, Issue 22, pp. 5961-75, (2014) (PubMed).

Savard, Lavoie, Brochu, Grbic, Lepage, Gris, Sebire: "Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy." in: Journal of neuroinflammation, Vol. 10, pp. 110, (2014) (PubMed).

Brochu, Girard, Lavoie, Sébire: "Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study." in: Journal of neuroinflammation, Vol. 8, pp. 55, (2011) (PubMed).

Synonyms and alternative names related to TBCE

tubulin-specific chaperone E (Tbce), tubulin folding cofactor E (TBCE), tubulin folding cofactor E (Tbce), 2610206D02Rik, C530005D02Rik, HRD, KCS, KCS1, pac2, pmn

Protein level used designations for TBCE

  • progressive motor neuropathy
  • tubulin-folding cofactor E
  • Kenny-Caffey syndrome
  • tubulin-specific chaperone E
  • beta-tubulin cofactor E
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