TARBP2 抗体
(TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008].
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Latest Publications for our TARBP2 抗体
: "Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins." in: Nature, Vol. 513, Issue 7517, pp. 256-60, (2014) (PubMed).: "A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma." in: Cancer cell, Vol. 21, Issue 6, pp. 807-21, (2012) (PubMed).
: "Viral RNAi suppressor reversibly binds siRNA to outcompete Dicer and RISC via multiple turnover." in: Journal of molecular biology, Vol. 408, Issue 2, pp. 262-76, (2011) (PubMed).
: "A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment." in: Nature cell biology, Vol. 10, Issue 8, pp. 987-93, (2008) (PubMed).
: "Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production." in: Journal of virology, Vol. 81, Issue 10, pp. 5121-31, (2007) (PubMed).
: "TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing." in: EMBO reports, Vol. 6, Issue 10, pp. 961-7, (2005) (PubMed).
: "Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30265-73, (2004) (PubMed).
: "Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4201-8, (1996) (PubMed).
: "The cellular factor TRP-185 regulates RNA polymerase II binding to HIV-1 TAR RNA." in: The EMBO journal, Vol. 14, Issue 23, pp. 5995-6009, (1996) (PubMed).
: "Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR." in: Science (New York, N.Y.), Vol. 251, Issue 5001, pp. 1597-600, (1991) (PubMed).
Aliases for TARBP2 抗体
TAR (HIV-1) RNA binding protein 2 (tarbp2) 抗体TARBP2, RISC loading complex RNA binding subunit (TARBP2) 抗体
TAR (HIV-1) RNA binding protein 2 L homeolog (tarbp2.L) 抗体
TARBP2, RISC loading complex RNA binding subunit (Tarbp2) 抗体
TAR (HIV) RNA binding protein 2 (tarbp2) 抗体
fj51e12 抗体
LOQS 抗体
MGC97783 抗体
Prbp 抗体
TARBP2 抗体
trbp 抗体
TRBP 抗体
trbp1 抗体
TRBP1 抗体
trbp2 抗体
TRBP2 抗体
wu:fj51e12 抗体
zgc:63778 抗体
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