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TAPBP 产品

(TAP Binding Protein (Tapasin) (TAPBP))
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured TAPBP Categories

TAPBP 抗体

High quality antibodies with extensive validation data.

TAPBP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TAPBP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TAPBP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7260003
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6148848
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Pig, Sheep
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2782218
Quantity 100 μL
Datasheet Datasheet

Recommended TAPBP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken
Analytical Method Quantitative
Validations
Cat. No. ABIN1059557
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN1059558
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN1059562
Quantity 96 tests
Datasheet Datasheet

Recommended TAPBP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322148
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317188
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733221
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our TAPBP Products

Sokol, Koelzer, Rau, Karamitopoulou, Zlobec, Lugli: "Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer." in: Journal of translational medicine, Vol. 13, pp. 279, (2015) (PubMed).

Synonyms and alternative names related to TAPBP

TAP binding protein (tapasin), tandem duplicate 1 (tapbp.1), TAP binding protein (tapbp), TAP binding protein (TAPBP), TAP binding protein (Tapbp), D17Wsu91e, mhc1uda, mhc1ufa, NGS17, SI:dZ179B20.1, SI:dZ179B20.3, SI:dZ179B20.7, TAPA, tapbp, TAPBP, TPN, tpsn, TPSN, zgc:109814

Protein level used designations for TAPBP

  • tapasin
  • TAP binding protein
  • TAP-associated protein
  • TAP-binding protein
  • TPSN
  • NGS-17
  • TPN
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