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TAF11 产品

(TATA Box Binding Protein Associated Factor 11 (TAF11))

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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].

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Featured TAF11 Categories

TAF11 抗体

High quality antibodies with extensive validation data.

TAF11 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TAF11 抗体

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Reactivity
Application
Validations
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Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
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Cat. No. ABIN520677
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
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  • (2)
Cat. No. ABIN7172670
Quantity 100 μL
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Reactivity Human
Application WB
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Cat. No. ABIN1881867
Quantity 400 μL
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Recommended TAF11 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6211735
Quantity 96 tests
Datasheet Datasheet

Recommended TAF11 蛋白

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Reactivity
Source
Validations
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Datasheet
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Source Wheat germ
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Cat. No. ABIN1322072
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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  • (1)
Cat. No. ABIN1322070
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3127901
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TAF11 Products

Anish, Hossain, Jacobson, Takada: "Characterization of transcription from TATA-less promoters: identification of a new core promoter element XCPE2 and analysis of factor requirements." in: PLoS ONE, Vol. 4, Issue 4, pp. e5103, (2009) (PubMed).

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Guermah, Ge, Chiang, Roeder: "The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis." in: Molecular cell, Vol. 12, Issue 4, pp. 991-1001, (2003) (PubMed).

Mengus, Gangloff, Carré, Lavigne, Davidson: "The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10064-71, (2000) (PubMed).

Birck, Poch, Romier, Ruff, Mengus, Lavigne, Davidson, Moras: "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family." in: Cell, Vol. 94, Issue 2, pp. 239-49, (1998) (PubMed).

Synonyms and alternative names related to TAF11

TATA-box binding protein associated factor 11 (Taf11), TATA-box binding protein associated factor 11 (TAF11), 28kDa, 1110038O14Rik, AI115401, AL024207, AW552398, MGC:15243, PRO214, TAF2I, TAFII28

Protein level used designations for TAF11

  • TAF(II)28
  • TAFII-28
  • TFIID subunit p30-beta
  • transcription initiation factor TFIID 28 kDa subunit
  • transcription initiation factor TFIID subunit 11
  • TAFII28
  • TATA box binding protein (TBP)-associated factor 11
  • TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD
  • transcription initiation factor TFIID 28 kD subunit
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