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TACI 产品

(Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))

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The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].

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Featured TACI Categories

TACI 抗体

High quality antibodies with extensive validation data.

TACI ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TACI 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TACI 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC
Validations
  • (7)
Cat. No. ABIN7193634
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (5)
Cat. No. ABIN7193609
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN680488
Quantity 100 μL
Datasheet Datasheet

Recommended TACI ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970977
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN1672883
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1889340
Quantity 96 tests
Datasheet Datasheet

Recommended TACI 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275684
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN4369892
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN5954907
Quantity 200 μg
Datasheet Datasheet

Latest Publications for our TACI Products

Pinna, Dos Santos, Perce-da-Silva, da Silva, da Silva, Alves, Santos, de Oliveira Ferreira, Lima-Junior, Villa-Verde, De Luca, Carvalho-Pinto, Banic: "Correlation of APRIL with production of inflammatory cytokines during acute malaria in the Brazilian Amazon." in: Immunity, inflammation and disease, Vol. 6, Issue 2, pp. 207-220, (2019) (PubMed).

Chapellier, Peña-Martínez, Ramakrishnan, Eriksson, Safaee-Talkhoncheh, Orsmark-Pietras, Lilljebjörn, Högberg, Hagström-Andersson, Fioretos, Larsson, Järås: "Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells." in: Haematologica, (2019) (PubMed).

Egia-Mendikute, Arpa, Rosell-Mases, Corral-Pujol, Carrascal, Carrillo, Mora, Chapman, Panosa, Vives-Pi, Stratmann, Serreze, Verdaguer: "B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes." in: Frontiers in immunology, Vol. 10, pp. 1732, (2019) (PubMed).

Du, Jacobs, Arkatkar, Rawlings, Jackson: "Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 11, pp. 3258-3268, (2018) (PubMed).

Saulep-Easton, Vincent, Quah, Wei, Ting, Croce, Tam, Mackay: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).

Zang, Jiang, Li, DU, Niu: "Characteristics of CD4+CD25+Foxp3+ regulatory T cells in patients with multiple organ dysfunction syndrome." in: Experimental and therapeutic medicine, Vol. 11, Issue 5, pp. 1908-1912, (2016) (PubMed).

Hoffmann, Kuhn, Laurent, Hauck, Berer, Wendlinger, Krumbholz, Khademi, Olsson, Dreyling, Pfister, Alexander, Hiepe, Kümpfel, Crawford, Wekerle, Hohlfeld, Lichtenthaler, Meinl: "The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 2, pp. 542-52, (2015) (PubMed).

Muema, Macharia, Hassan, Mwaringa, Fegan, Berkley, Nduati, Urban: "Control of Viremia Enables Acquisition of Resting Memory B Cells with Age and Normalization of Activated B Cell Phenotypes in HIV-Infected Children." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1082-91, (2015) (PubMed).

Uslu, Coleman, Allman, Katsenelson, Bram, Alugupalli, Akkoyunlu: "Impaired B cell receptor signaling is responsible for reduced TACI expression and function in X-linked immunodeficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 8, pp. 3582-95, (2014) (PubMed).

Figgett, Fairfax, Vincent, Le Page, Katik, Deliyanti, Quah, Verma, Grumont, Gerondakis, Hertzog, OReilly, Strasser, Mackay: "The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death." in: Immunity, Vol. 39, Issue 3, pp. 573-83, (2013) (PubMed).

Synonyms and alternative names related to TACI

TNF receptor superfamily member 13B (TNFRSF13B), tumor necrosis factor receptor superfamily, member 13b (Tnfrsf13b), TNF receptor superfamily member 13B (Tnfrsf13b), 1200009E08Rik, CD267, CVID, CVID2, RYZN, TACI, Taci, TNFRSF13B, TNFRSF14B

Protein level used designations for TACI

  • transmembrane activator and CAML interactor
  • tumor necrosis factor receptor 13B
  • tumor necrosis factor receptor superfamily member 13B
  • tumor necrosis factor receptor superfamily, member 13B
  • transmembrane activator and calcium-modulating and cyclophilin ligand interactor
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