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TAB2 产品

(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

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The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008].

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Featured TAB2 Categories

TAB2 抗体

High quality antibodies with extensive validation data.

TAB2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended TAB2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN2779619
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6735781
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (3)
  • (2)
Cat. No. ABIN969430
Quantity 100 μL
Datasheet Datasheet

Recommended TAB2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970604
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6227571
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6227570
Quantity 96 tests
Datasheet Datasheet

Recommended TAB2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125346
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3073632
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136942
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TAB2 Products

Lei, Han, Xiao, Jin, He, Wang: "Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex." in: Journal of virology, Vol. 88, Issue 17, pp. 9830-41, (2014) (PubMed).

Thienpont, Zhang, Postma, Breckpot, Tranchevent, Van Loo, Møllgård, Tommerup, Bache, Tümer, van Engelen, Menten, Mortier, Waggoner, Gewillig, Moreau, Devriendt, Larsen: "Haploinsufficiency of TAB2 causes congenital heart defects in humans." in: American journal of human genetics, Vol. 86, Issue 6, pp. 839-49, (2010) (PubMed).

Häcker, Karin: "Regulation and function of IKK and IKK-related kinases." in: Science's STKE : signal transduction knowledge environment, Vol. 2006, Issue 357, pp. re13, (2006) (PubMed).

Simmonds, Heward, Carr-Smith, Foxall, Franklyn, Gough: "Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 3, pp. 1056-61, (2006) (PubMed).

Cashin, Sci: "Two terms--one meaning: the conundrum of contemporary nomenclature in autism." in: Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, Vol. 19, Issue 3, pp. 137-44, (2006) (PubMed).

Synonyms and alternative names related to TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2 (TAB2), TGF-beta activated kinase 1/MAP3K7 binding protein 2 (Tab2), TGF-beta activated kinase 1/MAP3K7 binding protein 2 (tab2), 1110030N06Rik, A530078N03Rik, CHTD2, MAP3K7IP2, Map3k7ip2, map3k7ip2, mKIAA0733, zgc:77446

Protein level used designations for TAB2

  • TGF-beta activated kinase 1/MAP3K7 binding protein 2
  • mitogen-activated protein kinase kinase kinase 7-interacting protein 2-like
  • TAB-2
  • TAK1-binding protein 2
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
  • TGF-beta-activated kinase 1-binding protein 2
  • mitogen-activated protein kinase kinase kinase 7-interacting protein 2
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 2
  • Tak1 binding protein 2
  • mitogen activated protein kinase kinase kinase 7 interacting protein 2
  • mitogen-activated protein kinase kinase kinase 7-interacting protein 2 homolog
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