TAB1 抗体
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
TAB1 抗体 by 适用
Find TAB1 抗体 for a variety of species such as anti-Human TAB1, anti-Mouse TAB1, anti-Rat TAB1. The species listed below are among those available. Click on a link to go to the corresponding products.
TAB1 抗体 by 抗体来源
Find TAB1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
TAB1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal TAB1 抗体. Click on a link to go to the corresponding products.
TAB1 抗体 by 克隆
Find TAB1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular TAB1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (6)
Cat. No.
ABIN564552
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN7171965
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN523851
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (3)
Cat. No.
ABIN6148795
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
- (1)
Cat. No.
ABIN801873
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7101518
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN523849
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6263110
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
- (2)
Cat. No.
ABIN2855576
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IP
Validations
- (1)
Cat. No.
ABIN523850
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6743724
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN634348
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN1859749
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, EIA
Validations
- (2)
Cat. No.
ABIN500859
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN754348
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our TAB1 抗体
: "MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 ..." in: Frontiers in immunology, Vol. 8, pp. 1915, (2017) (PubMed).: "PRAK is essential for ras-induced senescence and tumor suppression." in: Cell, Vol. 128, Issue 2, pp. 295-308, (2007) (PubMed).
: "Determinants that control the specific interactions between TAB1 and p38alpha." in: Molecular and cellular biology, Vol. 26, Issue 10, pp. 3824-34, (2006) (PubMed).
: "TAK1-binding protein 1 is a pseudophosphatase." in: The Biochemical journal, Vol. 399, Issue 3, pp. 427-34, (2006) (PubMed).
: "Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex ..." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 7359-68, (2005) (PubMed).
: "Toll-like receptor signalling." in: Nature reviews. Immunology, Vol. 4, Issue 7, pp. 499-511, (2004) (PubMed).
: "Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol." in: Molecular and cellular biology, Vol. 22, Issue 20, pp. 7158-67, (2002) (PubMed).
: "TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages." in: FEBS letters, Vol. 467, Issue 2-3, pp. 160-4, (2000) (PubMed).
Aliases for TAB1 抗体
TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1) 抗体TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) 抗体
3'-Tab1 抗体
2310012M03Rik 抗体
b2b449Clo 抗体
MAP3K7IP1 抗体
Map3k7ip1 抗体
您还需要查找其他产品吗？
You are here:
