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SUPT5H 抗体

(Transcription Elongation Factor SPT5 (SUPT5H))
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
SUPT5H 抗体  (AA 981-1087) SUPT5H 抗体  (AA 981-1087) SUPT5H 抗体 (AA 981-1087) (ABIN520620)

SUPT5H 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated

SUPT5H 抗体  (AA 892-941) SUPT5H 抗体  (AA 892-941) SUPT5H 抗体 (AA 892-941) (ABIN6735860)

SUPT5H 适用: 人, 小鼠, 犬, Cow, 大鼠, 兔, 马, 豚鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

SUPT5H 抗体  (C-Term) SUPT5H 抗体  (C-Term) SUPT5H 抗体 (C-Term) (ABIN2777903)

SUPT5H 适用: 人, 犬, Cow, 兔, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

SUPT5H 抗体 by 适用

Find SUPT5H 抗体 for a variety of species such as anti-Human SUPT5H, anti-Mouse SUPT5H, anti-Dog SUPT5H. The species listed below are among those available. Click on a link to go to the corresponding products.

SUPT5H 抗体 by 应用范围

Find SUPT5H 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SUPT5H 抗体 by 抗体来源

Find SUPT5H 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SUPT5H 抗体 by 抗原表位

Find SUPT5H 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SUPT5H 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SUPT5H 抗体. Click on a link to go to the corresponding products.

SUPT5H 抗体 by 克隆

Find SUPT5H 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SUPT5H 抗体 by 标记

Find SUPT5H 抗体 with a specific conjugate such as APC, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SUPT5H 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN520620
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6735860
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN2777903
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN6740366
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6148739
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN2778245
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF (cc)
Validations
Cat. No. ABIN6989707
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (fp)
Validations
Cat. No. ABIN7454524
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7452446
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
Cat. No. ABIN7448819
Quantity 25 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA
Validations
Cat. No. ABIN7095118
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application IP
Validations
Cat. No. ABIN1937999
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IF, IHC (p)
Validations
Cat. No. ABIN1938000
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN2572517
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1938003
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our SUPT5H 抗体

Lu, Xue, Xue, Yu, Arias, Lin, Fong, Faure, Weisburd, Ji, Mercier, Sutton, Luo, Gao, Zhou: "Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism." in: eLife, Vol. 4, pp. e06535, (2015) (PubMed).

Arabi, Ullah, Branca, Johansson, Bandarra, Haneklaus, Fu, Ariës, Nilsson, Den Boer, Pokrovskaja, Grandér, Xiao, Rocha, Lehtiö, Sangfelt: "Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway." in: Nature communications, Vol. 3, pp. 976, (2012) (PubMed).

Ueki, Lin, Senoo, Ebihara, Agata, Onji, Saheki, Kawai, Mukherjee, Reichenberger, Olsen: "Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice." in: Cell, Vol. 128, Issue 1, pp. 71-83, (2007) (PubMed).

Amir-Zilberstein, Ainbinder, Toube, Yamaguchi, Handa, Dikstein: "Differential regulation of NF-kappaB by elongation factors is determined by core promoter type." in: Molecular and cellular biology, Vol. 27, Issue 14, pp. 5246-59, (2007) (PubMed).

Aliases for SUPT5H 抗体

SPT5 homolog, DSIF elongation factor subunit (SUPT5H) 抗体
transcription elongation factor SPT5 (LOC413814) 抗体
Transcription elongation factor Spt5 (AT2G34210) 抗体
transcription elongation factor Spt5 (spt5) 抗体
transcription elongation factor spt5 (MGYG_08422) 抗体
transcription elongation factor spt5 (TERG_05483) 抗体
hypothetical protein (PGTG_18458) 抗体
SPT5 homolog, DSIF elongation factor subunit (supt5h) 抗体
SPT5 homolog, DSIF elongation factor subunit (Supt5h) 抗体
SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S) 抗体
CG7626 gene product from transcript CG7626-RA (Spt5) 抗体
Transcription elongation factor SPT5 (spt-5) 抗体
transcription elongation factor (SPT5) 抗体
CaO19.1453 抗体
CG7626 抗体
dDSIF 抗体
Dmel\\CG7626 抗体
DSIF 抗体
Dspt5 抗体
dSpt5 抗体
etID10129.15 抗体
etID37101.15 抗体
F13P17.5 抗体
F13P17_5 抗体
fb37g01 抗体
fb95e05 抗体
fog 抗体
foggy 抗体
SPT5 抗体
Spt5 抗体
spt5 抗体
SPT5H 抗体
spt5h 抗体
Tat-CT1 抗体
tat-ct1 抗体
wu:fb37g01 抗体
wu:fb95e05 抗体
wu:fc10f02 抗体
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