SUN2 产品
(Sad1 and UNC84 Domain Containing 2 (SUN2))
Categories
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1\; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010].
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Featured SUN2 Categories
Recommended SUN2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (8)
Cat. No.
ABIN7075502
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7270136
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7170975
Quantity
100 μg
Datasheet
Datasheet
Recommended SUN2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324663
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118899
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136192
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SUN2 Products
: "Samp1 is a component of TAN lines and is required for nuclear movement." in: Journal of cell science, Vol. 125, Issue Pt 5, pp. 1099-105, (2012) (PubMed).: "Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes." in: The Journal of biological chemistry, Vol. 285, Issue 5, pp. 3487-98, (2010) (PubMed).
Synonyms and alternative names related to SUN2
Sad1 and UNC84 domain containing 2 (SUN2), Sad1 and UNC84 domain containing 2 (Sun2), B230369L08Rik, C030011B15, RGD1563141, UNC84B, Unc84bProtein level used designations for SUN2
- SUN domain-containing protein 2
- Sad1 unc-84 domain protein 2
- nuclear envelope protein
- protein unc-84 homolog B
- rab5-interacting protein
- rab5IP
- sad1/unc-84 protein-like 2
- unc-84 homolog B
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