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STK39 产品

(serine threonine Kinase 39 (STK39))
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008].

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Featured STK39 Categories

STK39 抗体

High quality antibodies with extensive validation data.

STK39 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

STK39 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STK39 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (6)
Cat. No. ABIN7101461
Quantity 20 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
  • (7)
Cat. No. ABIN392497
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN570996
Quantity 100 μg
Datasheet Datasheet

Recommended STK39 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970113
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6959385
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381528
Quantity 96 tests
Datasheet Datasheet

Recommended STK39 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1321704
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409908
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3077459
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our STK39 Products

Mao, Ladd, Gad, Rastetter, Johnson, Marzbani, Childs, Lu, Dang, Broussard, Stanton, Hanash, Disis: "Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer." in: Journal of translational medicine, Vol. 12, pp. 121, (2014) (PubMed).

Yang, Cai, Zhou, Chen, Chen, Chen, Wang, Fang, Zhou: "STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy." in: PLoS ONE, Vol. 8, Issue 9, pp. e74614, (2013) (PubMed).

Arion, Lewis: "Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia." in: Archives of general psychiatry, Vol. 68, Issue 1, pp. 21-31, (2011) (PubMed).

Wang, OConnell, McArdle, Wade, Dorff, Shah, Shi, Pan, Rampersaud, Shen, Kim, Subramanya, Steinle, Parsa, Ober, Welling, Chakravarti, Weder, Cooper, Mitchell, Shuldiner, Chang: "From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 1, pp. 226-31, (2009) (PubMed).

Smith, Smallwood, Altman, Liedtke: "PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells." in: The Journal of biological chemistry, Vol. 283, Issue 32, pp. 22147-56, (2008) (PubMed).

Ramoz, Cai, Reichert, Silverman, Buxbaum: "An analysis of candidate autism loci on chromosome 2q24-q33: evidence for association to the STK39 gene." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 7, pp. 1152-8, (2008) (PubMed).

Yan, Nguyen, Dalmasso, Sitaraman, Merlin: "Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform." in: Biochimica et biophysica acta, Vol. 1769, Issue 2, pp. 106-16, (2007) (PubMed).

Polek, Talpaz, Spivak-Kroizman: "TRAIL-induced cleavage and inactivation of SPAK sensitizes cells to apoptosis." in: Biochemical and biophysical research communications, Vol. 349, Issue 3, pp. 1016-24, (2006) (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).

Liedtke, Wang, Smallwood: "Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function." in: The Journal of biological chemistry, Vol. 280, Issue 27, pp. 25491-8, (2005) (PubMed).

Synonyms and alternative names related to STK39

serine/threonine kinase 39 (stk39), serine/threonine kinase 39 (STK39), serine/threonine kinase 39 L homeolog (stk39.L), serine threonine kinase 39 (Stk39), serine threonine kinase 39 (STK39), serine/threonine kinase 39 (Stk39), AW227544, AW556857, dcht, DCHT, MGC69537, pask, PASK, RF005, Rnl5, spak, SPAK, Spak

Protein level used designations for STK39

  • serine threonine kinase 39 (STE20/SPS1 homolog)
  • serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
  • serine threonine kinase 39
  • serine/threonine kinase 39
  • STE20/SPS1 homolog
  • STE20/SPS1-related proline-alanine-rich protein kinase
  • Ste20-like protein kinase
  • proline-alanine-rich STE20-related kinase
  • serine/threonine-protein kinase 39
  • small intestine SPAK-like kinase
  • ste-20-related kinase
  • PS/TK
  • PSTK1
  • Ste-20 related kinase
  • pancreatic serine/threonine-protein kinase
  • kidney-specific SPAK
  • serine/threonine kinase 39, STE20/SPS1 homolog
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