Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 产品
(Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
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This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008].
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Featured Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Categories
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 抗体
High quality antibodies with extensive validation data.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN520465
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7270595
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Pig, Rabbit
Application
WB, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN2781788
Quantity
100 μL
Datasheet
Datasheet
Recommended Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959725
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962626
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959723
Quantity
96 tests
Datasheet
Datasheet
Recommended Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321302
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409836
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409833
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Products
: "TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model." in: Neuropharmacology, Vol. 111, pp. 142-159, (2016) (PubMed).: "The role of 5α-reductase type 1 associated with intratumoral dihydrotestosterone concentrations in human endometrial carcinoma." in: Molecular and cellular endocrinology, Vol. 401, pp. 56-64, (2015) (PubMed).
: "Hamster SRD5A3 lacks steroid 5α-reductase activity in vitro." in: Steroids, Vol. 94, pp. 41-50, (2015) (PubMed).
: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).
: "Resistance training restores muscle sex steroid hormone steroidogenesis in older men." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 4, pp. 1891-7, (2014) (PubMed).
: "Seoritae extract reduces prostate weight and suppresses prostate cell proliferation in a rat model of benign prostate hyperplasia." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 475876, (2014) (PubMed).
: "46,XY disorder of sexual development resulting from a novel monoallelic mutation (p.Ser31Phe) in the steroid 5α-reductase type-2 (SRD5A2) gene." in: Molecular genetics & genomic medicine, Vol. 2, Issue 4, pp. 292-6, (2014) (PubMed).
: "DHEA administration activates local bioactive androgen metabolism in cancellous site of tibia of ovariectomized rats." in: Calcified tissue international, Vol. 89, Issue 2, pp. 105-10, (2011) (PubMed).
: "Molecular analysis of the SRD5A2 in 46,XY subjects with incomplete virilization: the P212R substitution of the steroid 5alpha-reductase 2 may constitute an ancestral founder mutation in Mexican ..." in: Journal of andrology, Vol. 31, Issue 4, pp. 358-64, (2010) (PubMed).
: "VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 10, pp. 3223-9, (2008) (PubMed).
Synonyms and alternative names related to Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
steroid 5 alpha-reductase 2 (SRD5A2), steroid 5 alpha-reductase 2 (Srd5a2), steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (srd5a2), 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (LOC100125532), steroid-5-alpha-reductase, alpha polypeptide 2a (srd5a2a), steroid-5-alpha-reductase, alpha polypeptide 2b (srd5a2b), 5ART2, CH73-233A22.6, S5AR 2, SRD5A2, Srd5a2, SRD5alpha2, wu:fk70d02, zgc:109942, zgc:112208, zgc:112455Protein level used designations for Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- 5 alpha-SR2
- S5AR 2
- SR type 2
- steroid 5-alpha-reductase 2
- type II 5-alpha reductase
- steroid 5 alpha reductase type2
- prostatic steroid 5-alpha-reductase type II
- steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- steroid-5-alpha-reductase alpha polypeptide 2
- steroid-5-alpha-reductase, alpha polypeptide 2b
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