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STEAP4 产品

(STEAP Family Member 4 (STEAP4))

Categories

The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011].

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Featured STEAP4 Categories

STEAP4 抗体

High quality antibodies with extensive validation data.

STEAP4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STEAP4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7192673
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7270588
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN6265335
Quantity 100 μL
Datasheet Datasheet

Recommended STEAP4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207671
Quantity 96 tests
Datasheet Datasheet

Recommended STEAP4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131967
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3115570
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3127741
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our STEAP4 Products

Xue, Bredell, Anderson, Martin, Mays, Nagao-Kitamoto, Huang, Győrffy, Greenson, Hardiman, Spence, Kamada, Shah: "Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 45, pp. E9608-E9617, (2018) (PubMed).

Chuang, Guh, Lu, Wang, Chen, Chuang: "Steap4 attenuates high glucose and S100B-induced effects in mesangial cells." in: Journal of cellular and molecular medicine, Vol. 19, Issue 6, pp. 1234-44, (2015) (PubMed).

Wellen, Fucho, Gregor, Furuhashi, Morgan, Lindstad, Vaillancourt, Gorgun, Saatcioglu, Hotamisligil: "Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis." in: Cell, Vol. 129, Issue 3, pp. 537-48, (2007) (PubMed).

Ohgami, Campagna, McDonald, Fleming: "The Steap proteins are metalloreductases." in: Blood, Vol. 108, Issue 4, pp. 1388-94, (2006) (PubMed).

Korkmaz, Korkmaz, Kurys, Elbi, Wang, Klokk, Hammarstrom, Troen, Svindland, Hager, Saatcioglu: "Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer." in: Oncogene, Vol. 24, Issue 31, pp. 4934-45, (2005) (PubMed).

Synonyms and alternative names related to STEAP4

STEAP4 metalloreductase (STEAP4), STEAP4 metalloreductase L homeolog (steap4.L), STEAP4 metalloreductase (Steap4), STEAP4 metalloreductase (steap4), metalloreductase STEAP4 (LOC100136336), metalloreductase STEAP4 (LOC100353852), STEAP family member 4 (Steap4), STEAP family member 4 (steap4), 1110021O17Rik, AI481214, MGC68826, MGC108044, si:dkey-53p21.1, STAMP2, STEAP4, steap4, TIARP, Tiarp, TNFAIP9, Tnfaip9, zgc:112143

Protein level used designations for STEAP4

  • metalloreductase STEAP4
  • six transmembrane prostate protein 2
  • six-transmembrane epithelial antigen of prostate 4
  • sixTransMembrane protein of prostate 2
  • tumor necrosis factor, alpha-induced protein 9
  • tumor necrosis-alpha-induced adipose-related protein
  • STEAP family member 4
  • Ab1-219
  • six transmembrane epithelial antigen of the prostate 4
  • metalloreductase STEAP4-like
  • Tnfa-induced adipose-related protein
  • dudulin 4
  • dudulin-4
  • tumor necrosis factor-alpha-induced adipose-related protein
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