STAT5B 抗体
(Signal Transducer and Activator of Transcription 5B (STAT5B))
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
STAT5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
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Cat. No.
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Cat. No.
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Quantity
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Latest Publications for our STAT5B 抗体
: "Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells." in: Nature communications, Vol. 8, Issue 1, pp. 1320, (2018) (PubMed).: "TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells." in: European journal of immunology, Vol. 46, Issue 2, pp. 360-71, (2016) (PubMed).
: "BCR-ABL affects STAT5A and STAT5B differentially." in: PLoS ONE, Vol. 9, Issue 5, pp. e97243, (2015) (PubMed).
: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
: "Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A." in: Cancer cell international, Vol. 15, pp. 30, (2015) (PubMed).
: "A novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (Stat5) tyrosine phosphorylation and the selective influence of Stat5B over mast cell cytokine production." in: The Journal of biological chemistry, (2011) (PubMed).
: "Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors." in: The Journal of cell biology, Vol. 175, Issue 6, pp. 937-46, (2006) (PubMed).
: "Role of Stat5 in type I interferon-signaling and transcriptional regulation." in: Biochemical and biophysical research communications, Vol. 308, Issue 2, pp. 325-30, (2003) (PubMed).
: "Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5." in: The Journal of allergy and clinical immunology, Vol. 112, Issue 1, pp. 93-101, (2003) (PubMed).
: "Constitutive activation of Stat5b contributes to carcinogenesis in vivo." in: Cancer research, Vol. 63, Issue 20, pp. 6763-71, (2003) (PubMed).
Aliases for STAT5B 抗体
signal transducer and activator of transcription 5B (STAT5B) 抗体signal transducer and activator of transcription 5B (Stat5b) 抗体
signal transducer and activator of transcription 5B S homeolog (stat5b.S) 抗体
signal transducer and activator of transcription 5B (LOC490969) 抗体
Signal transducer and activator of transcription 5B (sta5b) 抗体
signal transducer and activator of transcription 5B (LOC100566752) 抗体
signal transducer and activator of transcription 5B (LOC100052954) 抗体
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