STAT5A 产品
(Signal Transducer and Activator of Transcription 5A (STAT5A))
Categories
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008].
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Featured STAT5A Categories
STAT5A 抗体
High quality antibodies with extensive validation data.
STAT5A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
STAT5A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended STAT5A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF (cc)
Validations
- (3)
- (1)
Cat. No.
ABIN5557532
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN1098129
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (6)
Cat. No.
ABIN950127
Quantity
50 μg
Datasheet
Datasheet
Recommended STAT5A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN1981843
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN1981730
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959477
Quantity
96 tests
Datasheet
Datasheet
Recommended STAT5A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321600
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321602
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417432
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our STAT5A Products
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).: "STAT3, STAT5A, STAT5B and STAT6 proteins are overexpressed in human basal cell carcinoma." in: Clinical and experimental dermatology, (2019) (PubMed).
: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).
: "TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells." in: European journal of immunology, Vol. 46, Issue 2, pp. 360-71, (2016) (PubMed).
: "Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features." in: PLoS ONE, Vol. 9, Issue 8, pp. e104265, (2014) (PubMed).
: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).
: "Role of prolactin in B cell regulation in multiple sclerosis." in: Journal of neuroimmunology, Vol. 269, Issue 1-2, pp. 76-86, (2014) (PubMed).
: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, (2012) (PubMed).
: "Characterization of the rat oncostatin M receptor complex which resembles the human, but differs from the murine cytokine receptor." in: PLoS ONE, Vol. 7, Issue 8, pp. e43155, (2012) (PubMed).
Synonyms and alternative names related to STAT5A
signal transducer and activator of transcription 5A (STAT5A), signal transducer and activator of transcription 5A (Stat5a), signal transducer and activator of transcription 5a (stat5a), signal transducer and activator of transcription 5A (LOC100348518), signal transducer and activator of transcription 5A (LOC100716811), AA959963, MGF, STAT5, Stat5, stat5, STAT5A, STAT5A/MGF, stat5b, STATA5Protein level used designations for STAT5A
- mammary gland factor STAT5A
- mammary gland factor
- signal transducer and activator of transcription 5
- STAT5A, Mammary Gland Factor
- signal transducer and activator of transcription 5A
- signal transducer and activator of transcription 5A-like
- signal transducer and activator of transcription 5B
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