STAT2 抗体
(Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
recommended
STAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
STAT2 抗体 by 适用
Find STAT2 抗体 for a variety of species such as anti-Human STAT2, anti-Mouse STAT2, anti-Rat STAT2. The species listed below are among those available. Click on a link to go to the corresponding products.
STAT2 抗体 by 抗体来源
Find STAT2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
STAT2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal STAT2 抗体. Click on a link to go to the corresponding products.
STAT2 抗体 by 克隆
Find STAT2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular STAT2 抗体
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Reactivity
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Validations
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Datasheet
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WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
100 μL
Datasheet
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Application
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Cat. No.
ABIN563025
Quantity
100 μg
Datasheet
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Reactivity
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Application
WB, IP, IHC (p)
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- (4)
Cat. No.
ABIN2855558
Quantity
100 μL
Datasheet
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Reactivity
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WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Chimpanzee, Cow, Dog, Horse, Human, Macaque, Mouse, Pig, Rat, Vervet Monkey
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Cat. No.
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Quantity
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Latest Publications for our STAT2 抗体
: "STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α." in: Scientific reports, Vol. 6, pp. 38336, (2018) (PubMed).: "Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2." in: Journal of virology, Vol. 91, Issue 10, (2017) (PubMed).
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
: "The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 4457-69, (2010) (PubMed).
: "Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2." in: The Journal of biological chemistry, Vol. 283, Issue 18, pp. 12034-42, (2008) (PubMed).
: "Suppression of interferon (IFN)-inducible genes and IFN-mediated functional responses in BCR-ABL-expressing cells." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10793-803, (2008) (PubMed).
: "Upregulation of a small subset of genes drives type I interferon-induced antiviral memory." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 27, Issue 8, pp. 653-64, (2007) (PubMed).
: "Stats: multifaceted regulators of transcription." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 25, Issue 12, pp. 733-44, (2005) (PubMed).
: "Functional relevance of the conserved DNA-binding domain of STAT2." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 13029-36, (2005) (PubMed).
: "STAT2 nuclear trafficking." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39199-206, (2004) (PubMed).
Aliases for STAT2 抗体
signal transducer and activator of transcription 2 (stat2) 抗体signal transducer and activator of transcription 2 (STAT2) 抗体
AGAP000099-PA (STAT2) 抗体
signal transducer and activator of transcription 2 (Stat2) 抗体
1600010G07Rik 抗体
AW496480 抗体
ISGF-3 抗体
p113 抗体
P113 抗体
stat2 抗体
STAT113 抗体
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