STAT1 产品
(Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
Categories
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured STAT1 Categories
STAT1 抗体
High quality antibodies with extensive validation data.
STAT1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
STAT1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended STAT1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
- (8)
Cat. No.
ABIN6256410
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7443806
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (6)
Cat. No.
ABIN7265092
Quantity
200 μL
Datasheet
Datasheet
Recommended STAT1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (2)
- (6)
Cat. No.
ABIN1981837
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN625230
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN625231
Quantity
96 tests
Datasheet
Datasheet
Recommended STAT1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667813
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321588
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321590
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our STAT1 Products
: "Renin-angiotensin system promotes colonic inflammation by inducing TH17 activation via JAK2/STAT pathway." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 316, Issue 6, pp. G774-G784, (2019) (PubMed).: "IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species." in: International immunopharmacology, Vol. 48, pp. 76-83, (2018) (PubMed).
: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).
: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone." in: Nature communications, Vol. 7, pp. 13885, (2018) (PubMed).
: "CT‑1042, a novel anticancer agent, exhibits effects by activating p53 and inhibiting survivin." in: Oncology reports, Vol. 39, Issue 6, pp. 2759-2768, (2018) (PubMed).
: "Hesperetin derivative-14 alleviates inflammation by activating PPAR-γ in mice with CCl4-induced acute liver injury and LPS-treated RAW264.7 cells." in: Toxicology letters, Vol. 274, pp. 51-63, (2017) (PubMed).
: "Inhibition of Src homology 2 domain containing protein tyrosine phosphatase as the possible mechanism of metformin-assisted amelioration of obesity induced insulin resistance in high fat diet fed ..." in: Biochemical and biophysical research communications, Vol. 487, Issue 1, pp. 54-61, (2017) (PubMed).
: "PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy." in: EMBO molecular medicine, Vol. 9, Issue 2, pp. 167-180, (2017) (PubMed).
: "The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1." in: American journal of physiology. Renal physiology, Vol. 310, Issue 11, pp. F1284-94, (2017) (PubMed).
Synonyms and alternative names related to STAT1
signal transducer and activator of transcription 1 (STAT1), signal transducer and activator of transcription 1 (Stat1), signal transducer and activator of transcription 1 L homeolog (stat1.L), signal transducer and activator of transcription 1, 91kDa (STAT1), signal transducer and activator of transcription 4 (stat4), signal transducer and activator of transcription 1a (stat1a), 2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, stat1, STAT4, STAT91, XStat1Protein level used designations for STAT1
- signal transducer and activator of transcription 1-alpha/beta
- signal transducer and activator of transcription-1
- transcription factor ISGF-3 components p91/p84
- signal transducer and activator of transcription 1
- signal transducer and activator of transcription 4
- transcription factor ISGF-3
- activator of transcription
- signal transduction
- LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta
- signal transducer and activator of transcription 1, 91kDa
- signal transduction and activation of transcription 1
- signal transduction and activation of transcription 1a
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