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ST5 产品

(Suppression of Tumorigenicity 5 (ST5))
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008].

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Featured ST5 Categories

ST5 抗体

High quality antibodies with extensive validation data.

ST5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ST5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ST5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7170987
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3187070
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6257500
Quantity 100 μL
Datasheet Datasheet

Recommended ST5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648096
Quantity 96 tests
Datasheet Datasheet

Recommended ST5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125252
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321495
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095650
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ST5 Products

Majidi, Gutkind, Lichy: "Deletion of the COOH terminus converts the ST5 p70 protein from an inhibitor of RAS signaling to an activator with transforming activity in NIH-3T3 cells." in: The Journal of biological chemistry, Vol. 275, Issue 9, pp. 6560-5, (2000) (PubMed).

Synonyms and alternative names related to ST5

suppression of tumorigenicity 5 (st5), suppression of tumorigenicity 5 (ST5), suppression of tumorigenicity 5 (St5), 2010004M01Rik, 2610305K15Rik, dennd2b, DENND2B, DKFZp459D1230, hts1, HTS1, p126, si:ch211-208c6.1, ST5, wu:fc11b09, zgc:91902

Protein level used designations for ST5

  • suppression of tumorigenicity 5
  • suppression of tumorigenicity 5 protein
  • DENN/MADD domain containing 2B
  • heLa tumor suppression 1
  • DENN domain-containing protein 2B
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