SREBF1 抗体
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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SREBF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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Find SREBF1 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Cat. No.
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Quantity
100 μg
Datasheet
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Cow, Goat, Horse, Human, Mouse, Rat
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WB, IHC
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Cat. No.
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Cat. No.
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Cat. No.
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Quantity
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Cat. No.
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Datasheet
Datasheet
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
ABIN6736120
Quantity
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Datasheet
Datasheet
Reactivity
Goat, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
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Datasheet
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Latest Publications for our SREBF1 抗体
: "Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet." in: Frontiers in cell and developmental biology, Vol. 9, pp. 628143, (2021) (PubMed).: "14-Deoxy-11,12-didehydroandrographolide suppresses adipogenesis of 3 T3-L1 preadipocytes by inhibiting CCAAT/enhancer-binding protein β activation and AMPK-mediated mitotic clonal expansion." in: Toxicology and applied pharmacology, Vol. 359, pp. 82-90, (2019) (PubMed).
: "Perilipin 5 promotes hepatic steatosis in dairy cows through increasing lipid synthesis and decreasing very low density lipoprotein assembly." in: Journal of dairy science, Vol. 102, Issue 1, pp. 833-845, (2019) (PubMed).
: "Sterol 12α-hydroxylase Aggravates Dyslipidemia by Activating the Ceramide/mTORC1/SREBP1C Pathway via FGF21 and FGF15." in: Gene expression, (2019) (PubMed).
: "Benzyl Isothiocyanate and Phenethyl Isothiocyanate Inhibit Adipogenesis and Hepatosteatosis in Mice with Obesity Induced by a High-Fat Diet." in: Journal of agricultural and food chemistry, Vol. 67, Issue 25, pp. 7136-7146, (2019) (PubMed).
: "Low abundance of mitofusin 2 in dairy cows with moderate fatty liver is associated with alterations in hepatic lipid metabolism." in: Journal of dairy science, Vol. 102, Issue 8, pp. 7536-7547, (2019) (PubMed).
: "Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 39, Issue 8, pp. 1574-1587, (2019) (PubMed).
: "Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells." in: Cell death & disease, Vol. 10, Issue 7, pp. 537, (2019) (PubMed).
: "Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells." in: Frontiers in pharmacology, Vol. 10, pp. 709, (2019) (PubMed).
: "Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats." in: Frontiers in endocrinology, Vol. 10, pp. 620, (2019) (PubMed).
Aliases for SREBF1 抗体
sterol regulatory element binding transcription factor 1 (SREBF1) 抗体sterol regulatory element binding transcription factor 1 (Srebf1) 抗体
sterol regulatory element binding transcription factor 1 L homeolog (srebf1.L) 抗体
sterol regulatory element binding protein-1 (SREBP-1) 抗体
sterol regulatory element binding transcription factor 1 (srebf1) 抗体
Sterol regulatory element Binding Protein (sbp-1) 抗体
ADD-1 抗体
ADD1 抗体
bHLHd1 抗体
D630008H06 抗体
SCREBP1 抗体
SREBF1 抗体
SREBP-1 抗体
SREBP-1a 抗体
SREBP-1c 抗体
SREBP-1C 抗体
SREBP1 抗体
Srebp1 抗体
srebp1 抗体
SREBP1c 抗体
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