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SRA1 产品

(Steroid Receptor RNA Activator 1 (SRA1))

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Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012].

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Featured SRA1 Categories

SRA1 抗体

High quality antibodies with extensive validation data.

SRA1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SRA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
  • (2)
Cat. No. ABIN969416
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6747630
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN967076
Quantity 0.1 mL
Datasheet Datasheet

Recommended SRA1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207637
Quantity 96 tests
Datasheet Datasheet

Recommended SRA1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125214
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131930
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2732656
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our SRA1 Products

Bozdagi, Sakurai, Dorr, Pilorge, Takahashi, Buxbaum: "Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice." in: PLoS ONE, Vol. 7, Issue 8, pp. e42422, (2012) (PubMed).

Khaleel, Dorheim, Duryee, Durbin, Bussey, Garvin, Klassen, Thiele, Anderson: "High-pressure distention of the saphenous vein during preparation results in increased markers of inflammation: a potential mechanism for graft failure." in: The Annals of thoracic surgery, Vol. 93, Issue 2, pp. 552-8, (2012) (PubMed).

Kim, Moradi, Yuan, Norris, Vaziri: "Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney." in: American journal of physiology. Renal physiology, Vol. 296, Issue 6, pp. F1297-306, (2009) (PubMed).

Chooniedass-Kothari, Hamedani, Troup, Hubé, Leygue: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).

Steffen, Faix, Resch, Linkner, Wehland, Small, Rottner, Stradal: "Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes." in: Molecular biology of the cell, Vol. 17, Issue 6, pp. 2581-91, (2006) (PubMed).

Chooniedass-Kothari, Emberley, Hamedani, Troup, Wang, Czosnek, Hube, Mutawe, Watson, Leygue: "The steroid receptor RNA activator is the first functional RNA encoding a protein." in: FEBS letters, Vol. 566, Issue 1-3, pp. 43-7, (2004) (PubMed).

Lanz, Chua, Barron, Söder, DeMayo, OMalley: "Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7163-76, (2003) (PubMed).

Synonyms and alternative names related to SRA1

steroid receptor RNA activator 1 (SRA1), steroid receptor RNA activator 1 (Sra1), steroid receptor RNA activator 1 (sra1), steroid receptor RNA activator 1 S homeolog (sra1.S), cytoplasmic FMR1 interacting protein 1 (CYFIP1), AA959952, pp7684, SRA, Sra, SRAP, Srap, STRAA1, Straa1, Strra1, zgc:86613

Protein level used designations for SRA1

  • steroid receptor RNA activator 1 (complexes with NCOA1)
  • steroid receptor RNA activator protein
  • steroid receptor coactivator
  • SRAP
  • steroid receptor RNA activator 1
  • cytoplasmic FMR1-interacting protein 1
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