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SPTLC1 抗体

(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
SPTLC1 抗体  (C-Term) SPTLC1 抗体  (C-Term) SPTLC1 抗体 (C-Term) (ABIN3187765)

SPTLC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

SPTLC1 抗体  (AA 143-473) SPTLC1 抗体  (AA 143-473) SPTLC1 抗体 (AA 143-473) (ABIN7436414)

SPTLC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

SPTLC1 抗体  (AA 37-310) SPTLC1 抗体  (AA 37-310) SPTLC1 抗体 (AA 37-310) (ABIN7168895)

SPTLC1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

SPTLC1 抗体 by 适用

Find SPTLC1 抗体 for a variety of species such as anti-Human SPTLC1, anti-Mouse SPTLC1, anti-Rat SPTLC1. The species listed below are among those available. Click on a link to go to the corresponding products.

SPTLC1 抗体 by 应用范围

Find SPTLC1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SPTLC1 抗体 by 抗体来源

Find SPTLC1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SPTLC1 抗体 by 抗原表位

Find SPTLC1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SPTLC1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SPTLC1 抗体. Click on a link to go to the corresponding products.

SPTLC1 抗体 by 克隆

Find SPTLC1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SPTLC1 抗体 by 标记

Find SPTLC1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SPTLC1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN3187765
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7436414
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7168895
Quantity 100 μL
Datasheet Datasheet
Reactivity Guinea Pig, Hamster, Human, Monkey, Mouse, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6738265
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN523984
Quantity 100 μg
Datasheet Datasheet

Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2782713
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6740984
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN3043056
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN389109
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN2179417
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN2179422
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2179419
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2179418
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2179420
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2806646
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SPTLC1 抗体

Klas, Copic, Direder, Laggner, Prucksamas, Gruber, Ankersmit, Mildner: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." in: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).

Wei, Yerokun, Leipelt, Haynes, Radhakrishna, Momin, Kelly, Park, Wang, Carton, Uhlinger, Merrill: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).

Medler, Petrusca, Lee, Hubbard, Berdyshev, Skirball, Kamocki, Schuchman, Tuder, Petrache: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." in: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).

Stachowitz, Alessandrini, Abeck, Ring, Behrendt: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).

Dawkins, Hulme, Brahmbhatt, Auer-Grumbach, Nicholson: "Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I." in: Nature genetics, Vol. 27, Issue 3, pp. 309-12, (2001) (PubMed).

He, Appel, Le: "Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum." in: Brain research, Vol. 909, Issue 1-2, pp. 187-93, (2001) (PubMed).

Hanada, Hara, Nishijima, Kuge, Dickson, Nagiec: "A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32108-14, (1998) (PubMed).

Weiss, Stoffel: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, (1997) (PubMed).

Aliases for SPTLC1 抗体

serine palmitoyltransferase 1 (SPT1) 抗体
serine palmitoyltransferase 1 (AFUA_6G00300) 抗体
Serine palmitoyltransferase 1 (PAS_FragB_0040) 抗体
serine palmitoyltransferase long chain base subunit 1 (SPTLC1) 抗体
serine palmitoyltransferase, long chain base subunit 1 (sptlc1) 抗体
serine palmitoyltransferase, long chain base subunit 1 L homeolog (sptlc1.L) 抗体
serine palmitoyltransferase, long chain base subunit 1 (Sptlc1) 抗体
serine palmitoyltransferase long chain base subunit 1 (Sptlc1) 抗体
Afu6g00300 抗体
ATSPT1 抗体
AW552086 抗体
C77762 抗体
E030036H05 抗体
HSAN1 抗体
HSN1 抗体
LBC1 抗体
LCB1 抗体
Lcb1 抗体
RGD1306617 抗体
SERINE PALMITOYLTRANSFERASE 1 抗体
serine palmitoyltransferase 1 抗体
SPT1 抗体
Spt1 抗体
SPTI 抗体
wu:fc75h04 抗体
wu:fp41c08 抗体
zgc:112247 抗体
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