SPTLC1 抗体
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
recommended
SPTLC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
SPTLC1 抗体 by 应用范围
Find SPTLC1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
SPTLC1 抗体 by 抗体来源
Find SPTLC1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
SPTLC1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SPTLC1 抗体. Click on a link to go to the corresponding products.
SPTLC1 抗体 by 克隆
Find SPTLC1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular SPTLC1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (6)
Cat. No.
ABIN3187765
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7436414
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7168895
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Hamster, Human, Monkey, Mouse, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6738265
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN523984
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN2782713
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6740984
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN3043056
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (2)
- (1)
Cat. No.
ABIN389109
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No.
ABIN2179417
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN2179422
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN2179419
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN2179418
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN2179420
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN2806646
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our SPTLC1 抗体
: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." in: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).
: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." in: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I." in: Nature genetics, Vol. 27, Issue 3, pp. 309-12, (2001) (PubMed).
: "Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum." in: Brain research, Vol. 909, Issue 1-2, pp. 187-93, (2001) (PubMed).
: "A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32108-14, (1998) (PubMed).
: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, (1997) (PubMed).
Aliases for SPTLC1 抗体
serine palmitoyltransferase 1 (SPT1) 抗体serine palmitoyltransferase 1 (AFUA_6G00300) 抗体
Serine palmitoyltransferase 1 (PAS_FragB_0040) 抗体
serine palmitoyltransferase long chain base subunit 1 (SPTLC1) 抗体
serine palmitoyltransferase, long chain base subunit 1 (sptlc1) 抗体
serine palmitoyltransferase, long chain base subunit 1 L homeolog (sptlc1.L) 抗体
serine palmitoyltransferase, long chain base subunit 1 (Sptlc1) 抗体
serine palmitoyltransferase long chain base subunit 1 (Sptlc1) 抗体
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