SPTA1 产品
(Spectrin alpha 1, Erythrocytic (SPTA1))
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Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008].
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Featured SPTA1 Categories
SPTA1 抗体
High quality antibodies with extensive validation data.
SPTA1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended SPTA1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
Cat. No.
ABIN6148401
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, Coat, StM
Validations
- (6)
Cat. No.
ABIN6940644
Quantity
100 μg
Datasheet
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Reactivity
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Cat. No.
ABIN7256054
Quantity
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Datasheet
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Recommended SPTA1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
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Validations
Cat. No.
ABIN5593058
Quantity
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Datasheet
Datasheet
Reactivity
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Analytical Method
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Validations
Cat. No.
ABIN6210223
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
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Validations
Cat. No.
ABIN6200069
Quantity
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Datasheet
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Latest Publications for our SPTA1 Products
: "7SL RNA in vertebrate red blood cells." in: RNA (New York, N.Y.), Vol. 24, Issue 7, pp. 908-914, (2018) (PubMed).: "Spectrin mutations cause spinocerebellar ataxia type 5." in: Nature genetics, Vol. 38, Issue 2, pp. 184-90, (2006) (PubMed).
Synonyms and alternative names related to SPTA1
spectrin, alpha, erythrocytic 1 (Spta1), spectrin alpha, erythrocytic 1 (Spta1), spectrin alpha, erythrocytic 1 (SPTA1), AF093576, AI451697, EL2, ha, HPP, HS3, ihj, nmf4, sph, SPH3, Spna-1, Spna1, SPTAProtein level used designations for SPTA1
- erythroid spectrin alpha
- spectrin alpha chain, erythrocyte
- alpha-spectrin 1, erythroid
- erythroid alpha-spectrin
- hemolytic anemia
- neuroscience mutagenesis facility, 4
- spectrin alpha 1
- spectrin alpha chain, erythrocytic 1
- spherocytosis
- alpha-I spectrin
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