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SPINT2 产品

(serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

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This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

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Featured SPINT2 Categories

SPINT2 抗体

High quality antibodies with extensive validation data.

SPINT2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SPINT2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPINT2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7436417
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7262667
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7157739
Quantity 100 μg
Datasheet Datasheet

Recommended SPINT2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959383
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510589
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510588
Quantity 96 tests
Datasheet Datasheet

Recommended SPINT2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098709
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321203
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7197930
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our SPINT2 Products

Zajaczkowska, Popiolek-Barczyk, Pilat, Rojewska, Makuch, Wordliczek, Mika: "Involvement of microglial cells in the antinociceptive effects of metamizol in a mouse model of neuropathic pain." in: Pharmacology, biochemistry, and behavior, Vol. 175, pp. 77-88, (2018) (PubMed).

Friis, Sales, Schafer, Vogel, Kataoka, Bugge: "The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22319-32, (2014) (PubMed).

Sivagnanam, Janecke, Müller, Heinz-Erian, Taylor, Bird: "Case of syndromic tufting enteropathy harbors SPINT2 mutation seen in congenital sodium diarrhea." in: Clinical dysmorphology, Vol. 19, Issue 1, pp. 48, (2009) (PubMed).

Synonyms and alternative names related to SPINT2

serine peptidase inhibitor, Kunitz type, 2 (Spint2), serine peptidase inhibitor, Kunitz type 2 (SPINT2), serine protease inhibitor, Kunitz type 2 (Spint2), AL024025, C76321, DIAR3, HAI-2, HAI2, Kop, Pb, PB

Protein level used designations for SPINT2

  • hepatocyte growth factor activator inhibitor type 2
  • placental bikunin
  • serine protease inhibitor, Kunitz type 2
  • kunitz-type protease inhibitor 2
  • serine protease inhibitor, Kunitz type, 2
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