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SPINK5 产品

(serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

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This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene.

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Featured SPINK5 Categories

SPINK5 抗体

High quality antibodies with extensive validation data.

Recommended SPINK5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7436423
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7439546
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7168929
Quantity 100 μg
Datasheet Datasheet

Recommended SPINK5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959381
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959382
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883598
Quantity 96 tests
Datasheet Datasheet

Recommended SPINK5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405765
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403660
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399232
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SPINK5 Products

Sugihara, Sugimoto, Tachibana, Kobashi, Nomura, Miyake, Hirai, Yamasaki, Morizane: "TNF-α and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes." in: Journal of dermatological science, Vol. 96, Issue 1, pp. 26-32, (2019) (PubMed).

McGovern, Meinert, de Veer, Hollier, Parker, Upton: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." in: The British journal of dermatology, (2016) (PubMed).

Synonyms and alternative names related to SPINK5

serine peptidase inhibitor, Kazal type 5 (Spink5), serine peptidase inhibitor, Kazal type 5 (SPINK5), 2310065D10Rik, AV238912, LEKT1, LEKTI, LETK1, LETKI, NETS, NS, VAKT1, VAKTI

Protein level used designations for SPINK5

  • serine protease inhibitor, Kazal type 5
  • lympho-epithelial Kazal-type-related inhibitor
  • lymphoepithelial Kazal-type-related inhibitor
  • serine protease inhibitor Kazal-type 5
  • Netherton syndrome
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