SPANXB1 抗体
(SPANX Family, Member B1 (SPANXB1))
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008].
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Reactivity
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Cat. No.
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Datasheet
Datasheet
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Application
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Quantity
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Application
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Quantity
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Application
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Quantity
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Datasheet
Datasheet
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Application
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our SPANXB1 抗体
: "SPANX gene variation in fertile and infertile males." in: Systems biology in reproductive medicine, Vol. 55, pp. 18-26, (2010) (PubMed).: "A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family." in: Molecular reproduction and development, Vol. 75, Issue 2, pp. 219-29, (2007) (PubMed).
: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." in: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).
: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." in: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).
Aliases for SPANXB1 抗体
SPANX family member B1 (SPANXB1) 抗体B1 抗体
CT11.2 抗体
SPANX-B 抗体
SPANXB 抗体
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