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SPACA1 产品

(Sperm Acrosome Associated 1 (SPACA1))
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008].

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Featured SPACA1 Categories

SPACA1 抗体

High quality antibodies with extensive validation data.

SPACA1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SPACA1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPACA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7170448
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7247705
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654730
Quantity 400 μL
Datasheet Datasheet

Recommended SPACA1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1159302
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1159303
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1159301
Quantity 96 tests
Datasheet Datasheet

Recommended SPACA1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321048
Quantity 10 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1623102
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SPACA1 Products

Streichemberger, Perrin, Saias-Magnan, Karsenty, Malzac, Grillo, Mitchell, Metzler-Guillemain: "Case report of apoptosis in testis of four AZFc-deleted patients: increased DNA fragmentation during meiosis, but decreased apoptotic markers in post-meiotic germ cells." in: Human reproduction (Oxford, England), Vol. 27, Issue 7, pp. 1939-45, (2012) (PubMed).

Longepied, Saut, Aknin-Seifer, Levy, Frances, Metzler-Guillemain, Guichaoua, Mitchell: "Complete deletion of the AZFb interval from the Y chromosome in an oligozoospermic man." in: Human reproduction (Oxford, England), Vol. 25, Issue 10, pp. 2655-63, (2010) (PubMed).

Synonyms and alternative names related to SPACA1

sperm acrosome associated 1 (SPACA1), sperm acrosome associated 1 (Spaca1), 1700124L11Rik, 4930540L03Rik, SAMP32

Protein level used designations for SPACA1

  • sperm acrosomal membrane-associated protein 32
  • sperm acrosome membrane-associated protein 1
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