SOCS1 抗体
(Suppressor of Cytokine Signaling 1 (SOCS1))
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008].
recommended
recommended
Verified SOCS1 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
recommended
SOCS1 抗体 by Grade
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SOCS1 抗体 by 适用
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SOCS1 抗体 by 克隆形成能力
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Latest Publications for our SOCS1 抗体
: "Poor stimulation of bovine dendritic cells by Mycobacterium bovis culture supernatant and surface extract is associated with decreased activation of ERK and NF-κB and higher expression of SOCS1 and 3." in: Innate immunity, Vol. 26, Issue 6, pp. 537-546, (2020) (PubMed).: "Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 443, (2018) (PubMed).
: "Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications." in: Oncotarget, Vol. 8, Issue 57, pp. 96958-96969, (2017) (PubMed).
: "Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model." in: European journal of pharmacology, Vol. 793, pp. 119-126, (2017) (PubMed).
: "TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection." in: Neurobiology of disease, Vol. 69, pp. 235-47, (2014) (PubMed).
: "SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor." in: PLoS ONE, Vol. 8, Issue 9, pp. e76370, (2013) (PubMed).
: "IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology." in: Cell, Vol. 144, Issue 4, pp. 601-13, (2011) (PubMed).
: "Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia." in: Nature medicine, Vol. 17, Issue 7, pp. 845-53, (2011) (PubMed).
: "The effects of HIF-1alpha on gene expression profiles of NCI-H446 human small cell lung cancer cells." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 150, (2010) (PubMed).
: "SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 8018-26, (2008) (PubMed).
Aliases for SOCS1 抗体
suppressor of cytokine signaling 1a (socs1a) 抗体suppressor of cytokine signaling 1 (socs1) 抗体
suppressor of cytokine signaling 1 (SOCS1) 抗体
suppressor of cytokine signaling 1 L homeolog (socs1.L) 抗体
suppressor of cytokine signaling 1 (Socs1) 抗体
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SOCS-1 抗体
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socs1 抗体
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ssi1 抗体
SSI1 抗体
tip3 抗体
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