SNRPN 抗体
(Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008].
recommended
recommended
SNRPN 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
recommended
SNRPN 抗体 by 应用范围
Find SNRPN 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
SNRPN 抗体 by 抗体来源
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SNRPN 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SNRPN 抗体. Click on a link to go to the corresponding products.
SNRPN 抗体 by 克隆
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SNRPN 抗体 by 标记
Find SNRPN 抗体 with a specific conjugate such as APC, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular SNRPN 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN3032638
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN6746188
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p), ICC
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- (3)
Cat. No.
ABIN3044164
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
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Cat. No.
ABIN520354
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7270366
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN6282178
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF
Validations
Cat. No.
ABIN7119175
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC (p)
Validations
Cat. No.
ABIN6992128
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Guinea Pig, Human, Monkey, Mouse, Pig, Rat, Sheep, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p), ICC
Validations
Cat. No.
ABIN2628584
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
Cat. No.
ABIN2572082
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
Cat. No.
ABIN7466866
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
Cat. No.
ABIN1937041
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
Cat. No.
ABIN1937042
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
Cat. No.
ABIN1937043
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
Cat. No.
ABIN1937044
Quantity
200 μL
Datasheet
Datasheet
Latest Publications for our SNRPN 抗体
: "A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein." in: PLoS ONE, Vol. 13, Issue 8, pp. e0201764, (2019) (PubMed).: "Urethral proteomic analysis in ovariectomized mice administered 17β-oestradiol replacement therapy." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, pp. 1-9, (2017) (PubMed).
: "Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22." in: Disease models & mechanisms, Vol. 10, Issue 3, pp. 215-224, (2017) (PubMed).
: "Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish." in: Scientific reports, Vol. 6, pp. 27470, (2016) (PubMed).
: "Effect of small nuclear ribonucleoprotein-associated polypeptide N on the proliferation of medulloblastoma cells." in: Molecular medicine reports, Vol. 11, Issue 5, pp. 3337-43, (2015) (PubMed).
: "Systematic identification of novel SLE related autoantibodies responsible for type I IFN production in human plasmacytoid dendritic cells." in: Cellular immunology, Vol. 284, Issue 1-2, pp. 119-28, (2013) (PubMed).
: "Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses." in: PLoS ONE, Vol. 6, Issue 8, pp. e24269, (2011) (PubMed).
: "Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 6, pp. 1959-64, (2007) (PubMed).
: "SMN, the product of the spinal muscular atrophy-determining gene, is expressed widely but selectively in the developing human forebrain." in: The Journal of comparative neurology, Vol. 497, Issue 5, pp. 808-16, (2006) (PubMed).
: "snRNAs contain specific SMN-binding domains that are essential for snRNP assembly." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2747-56, (2004) (PubMed).
Aliases for SNRPN 抗体
small nuclear ribonucleoprotein polypeptide-like (SNRPL) 抗体small nuclear ribonucleoprotein polypeptides B and B1 (snrpb) 抗体
small nuclear ribonucleoprotein polypeptide N (SNRPN) 抗体
small nuclear ribonucleoprotein N (Snrpn) 抗体
small nuclear ribonucleoprotein polypeptide N (Snrpn) 抗体
small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 (snrpn) 抗体
SNRPN upstream reading frame (SNURF) 抗体
Small nuclear ribonucleoprotein-associated protein N (SNRPN) 抗体
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