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SMG8 产品

(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))

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Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity).

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Featured SMG8 Categories

SMG8 抗体

High quality antibodies with extensive validation data.

Recommended SMG8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application IHC, ELISA
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Cat. No. ABIN7238174
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
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Cat. No. ABIN6744122
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Reactivity Human
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Cat. No. ABIN632938
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Recommended SMG8 蛋白

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Reactivity
Source
Validations
Cat. No.
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Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3136728
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Synonyms and alternative names related to SMG8

SMG8, nonsense mediated mRNA decay factor (SMG8), smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg8), Protein smg-8 (smg-8), 1200011M11Rik, C17orf71, C19H17orf71

Protein level used designations for SMG8

  • amplified in breast cancer gene 2 protein
  • protein SMG8
  • protein smg-8 homolog
  • smg-8 homolog, nonsense mediated mRNA decay factor
  • CG6729 gene product
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