SMG7 产品
(Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
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This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011].
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Featured SMG7 Categories
SMG7 抗体
High quality antibodies with extensive validation data.
SMG7 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SMG7 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMG7 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC
Validations
- (3)
Cat. No.
ABIN7166132
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, IHC, ICC
Validations
- (2)
Cat. No.
ABIN6259540
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1501000
Quantity
100 μL
Datasheet
Datasheet
Recommended SMG7 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648325
Quantity
96 tests
Datasheet
Datasheet
Recommended SMG7 蛋白
Latest Publications for our SMG7 Products
: "Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes." in: Genes & development, Vol. 28, Issue 22, pp. 2498-517, (2014) (PubMed).: "RNA surveillance is required for endoplasmic reticulum homeostasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 21, pp. 8079-84, (2012) (PubMed).
Synonyms and alternative names related to SMG7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg7), SMG7, nonsense mediated mRNA decay factor (SMG7), 9430023P16Rik, C1orf16, EST1C, mKIAA0250, SGA56MProtein level used designations for SMG7
- EST1-like protein C
- protein SMG7
- EST1 telomerase component homolog C
- breast cancer-associated antigen SGA-56M
- ever shorter telomeres 1C
- smg-7 homolog, nonsense mediated mRNA decay factor
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