SMAD4 抗体
(SMAD Family Member 4 (SMAD4))
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009].
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Popular SMAD4 抗体
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Application
WB, IP, CUT&RUN
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- (1)
Cat. No.
ABIN6972727
Quantity
100 μL
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Application
WB, ELISA, IF, PLA
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Cat. No.
ABIN561723
Quantity
100 μg
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WB, IHC, IP
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Cat. No.
ABIN7270340
Quantity
100 μL
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WB, ELISA, IHC, ICC, FACS
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Cat. No.
ABIN969403
Quantity
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WB, ELISA, IHC, IF, FACS
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Cat. No.
ABIN3032608
Quantity
0.4 mL
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Human
Application
WB, ELISA, IHC, IP
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- (4)
Cat. No.
ABIN7160238
Quantity
100 μg
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WB, ELISA, IF, IHC (p)
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Cat. No.
ABIN7209606
Quantity
100 μL
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Application
WB, IF
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Cat. No.
ABIN392165
Quantity
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Application
ELISA, IHC, IF, DB
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Cat. No.
ABIN3032606
Quantity
0.4 mL
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WB, IHC (p), IF (cc)
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Cat. No.
ABIN5557399
Quantity
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Validations
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Cat. No.
ABIN7441925
Quantity
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Datasheet
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Application
WB, ELISA, PLA
Validations
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Cat. No.
ABIN517638
Quantity
100 μg
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Datasheet
Reactivity
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Application
WB, IF, IHC (p), FACS
Validations
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Cat. No.
ABIN652388
Quantity
400 μL
Datasheet
Datasheet
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Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
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Cat. No.
ABIN2780673
Quantity
100 μL
Datasheet
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Reactivity
Human
Application
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Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SMAD4 抗体
: "Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein-Gremlin signaling pathways." in: The Journal of biological chemistry, Vol. 293, Issue 9, pp. 3039-3055, (2019) (PubMed).: "The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis." in: Nature communications, Vol. 7, pp. 13436, (2016) (PubMed).
: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." in: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).
: "Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 2601830, (2016) (PubMed).
: "Transforming growth factor-?3 regulates cell junction restructuring via MAPK-mediated mRNA destabilization and Smad-dependent protein degradation of junctional adhesion molecule B (JAM-B)." in: Biochimica et biophysica acta, Vol. 1849, Issue 6, pp. 601-11, (2015) (PubMed).
: "Molecular responses of radiation-induced liver damage in rats." in: Molecular medicine reports, Vol. 11, Issue 4, pp. 2592-600, (2015) (PubMed).
: "Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways." in: European journal of nutrition, Vol. 53, Issue 1, pp. 187-99, (2014) (PubMed).
: "Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model." in: Scientific reports, Vol. 4, pp. 5587, (2014) (PubMed).
: "Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway." in: The Journal of nutritional biochemistry, Vol. 25, Issue 6, pp. 675-82, (2014) (PubMed).
: "Proteomic analysis of differentially expressed proteins in vitamin C-treated AGS cells." in: BMC biochemistry, Vol. 14, pp. 24, (2014) (PubMed).
Aliases for SMAD4 抗体
SMAD family member 4 (SMAD4) 抗体Smad4 protein (smad4) 抗体
SMAD family member 4 (Smad4) 抗体
SMAD family member 4, gene 1 L homeolog (smad4.1.L) 抗体
AW743858 抗体
D18Wsu70e 抗体
DPC4 抗体
dpc4 抗体
JIP 抗体
jip 抗体
MADH4 抗体
Madh4 抗体
madh4 抗体
MYHRS 抗体
smad4 抗体
Xsmad4 抗体
xsmad4a 抗体
XSmad4alpha 抗体
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