SLC9A4 产品
(Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 (SLC9A4))
Categories
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of hyperosmolar-induced cell shrinkage in a sustained intracellular acidification-dependence manner. Activated by 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) in a sustained intracellular acidification-dependence manner. Affects potassium/proton exchange as well as sodium/proton and lithium/proton exchange. In basolateral cell membrane, participates in homeostatic control of intracellular pH, and may play a role in proton extrusion in order to achieve transepithelial HCO3(-) secretion. In apical cell membrane may be involved in mediating sodium absorption. Requires for normal levels of gastric acid secretion, secretory membrane development, parietal cell maturation and/or differentiation and at least secondarily for chief cell differentiation.
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Featured SLC9A4 Categories
Recommended SLC9A4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
ELISA, WB
Validations
Cat. No.
ABIN3172632
Quantity
100 μg
Datasheet
Datasheet
Recommended SLC9A4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3115604
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136272
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SLC9A4 Products
: "In silico mapping of quantitative trait loci (QTL) regulating the milk ionome in mice identifies a milk iron locus on chromosome 1." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 29, Issue 9-10, pp. 632-655, (2019) (PubMed).Synonyms and alternative names related to SLC9A4
solute carrier family 9 member A4 (SLC9A4), solute carrier family 9 member A4 (slc9a4), solute carrier family 9 (sodium/hydrogen exchanger), member 4 (Slc9a4), solute carrier family 9 member A4 (Slc9a4), AW990558, D730009J23Rik, NHE4, Nhe4, SLC9A2Protein level used designations for SLC9A4
- solute carrier family 9 (sodium/hydrogen exchanger), member 4
- Na+/H+ exchanger
- solute carrier family 9 (sodium/hydrogen exchanger), member 2
- sodium/hydrogen exchanger 4-like
- NHE-4
- Na(+)/H(+) exchanger 4
- sodium/hydrogen exchanger 4
- solute carrier family 9 member 4
- solute carrier family 9 (sodium/hydrogen exchanger)
- Solute carrier family 9 (sodium/hydrogen exchanger)
- solute carrier family 9 (sodium/hydrogen exchanger) isoform 4
- solute carrier family 9, member 4
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