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SLC9A3R1 产品

(Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

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This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009].

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Featured SLC9A3R1 Categories

SLC9A3R1 抗体

High quality antibodies with extensive validation data.

SLC9A3R1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC9A3R1 抗体

Product
Reactivity
Application
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Cat. No.
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Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), PLA
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  • (4)
Cat. No. ABIN522831
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN6265156
Quantity 100 μL
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Reactivity Human
Application WB, FACS
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Cat. No. ABIN652034
Quantity 400 μL
Datasheet Datasheet

Recommended SLC9A3R1 蛋白

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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1320545
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1320543
Quantity 10 μg
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Reactivity Human
Source HEK-293 Cells
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Cat. No. ABIN2732190
Quantity 20 μg
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Latest Publications for our SLC9A3R1 Products

Chen, Händel, Ngeow, Muller, Hühn, Yang, Heindl, Berbers, Hegazy, Kionke, Yehia, Sack, Bläser, Rensing-Ehl, Reifenberger, Keith, Travis, Merkenschlager, Kiess, Wittekind, Walker, Ehl, Aretz, Dustin et al.: "Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. ..." in: The Journal of allergy and clinical immunology, Vol. 139, Issue 2, pp. 607-620.e15, (2016) (PubMed).

Ji, Fan, Yuan, Zhang, Dong, Peng: "EBP50 inhibits pancreatic cancer cell growth and invasion by targeting the β-catenin/E-cadherin pathway." in: Experimental and therapeutic medicine, Vol. 10, Issue 4, pp. 1311-1316, (2015) (PubMed).

Wang, Qin, Zhu: "Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease." in: The Journal of international medical research, Vol. 43, Issue 5, pp. 629-38, (2015) (PubMed).

Yang, Singh, Cha, Chen, Sarker, Murtazina, Jin, Zachos, Patterson, Tse, Kovbasnjuk, Li, Donowitz: "NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16960-74, (2013) (PubMed).

Boratkó, Gergely, Csortos: "Cell cycle dependent association of EBP50 with protein phosphatase 2A in endothelial cells." in: PLoS ONE, Vol. 7, Issue 4, pp. e35595, (2012) (PubMed).

Heng, Cervero, Simon, Stephens, Li, Zhang, Paule, Rainczuk, Singh, Quinonero, Tapia, Velasquez, Salamonsen, Rombauts, Nie: "Proprotein convertase 5/6 is critical for embryo implantation in women: regulating receptivity by cleaving EBP50, modulating ezrin binding, and membrane-cytoskeletal interactions." in: Endocrinology, Vol. 152, Issue 12, pp. 5041-52, (2011) (PubMed).

Wang, Yang, Abou-Samra, Friedman: "NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding." in: Molecular pharmacology, Vol. 75, Issue 5, pp. 1189-97, (2009) (PubMed).

Morales, Takahashi, Momin, Adams, Chen, Georgescu: "NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands." in: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2527-37, (2007) (PubMed).

Kreimann, Morales, de Orbeta-Cruz, Takahashi, Adams, Liu, McCrea, Georgescu: "Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function." in: Oncogene, Vol. 26, Issue 36, pp. 5290-9, (2007) (PubMed).

Wheeler, Sneddon, Wang, Friedman, Romero: "NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors." in: The Journal of biological chemistry, Vol. 282, Issue 34, pp. 25076-87, (2007) (PubMed).

Synonyms and alternative names related to SLC9A3R1

SLC9A3 regulator 1 (SLC9A3R1), microRNA 3615 (MIR3615), solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a (slc9a3r1a), solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1), SLC9A3 regulator 1 (Slc9a3r1), SLC9A3 regulator 1 S homeolog (slc9a3r1.S), cb895, EBP-50, EBP50, NHE-RF, NHERF, nherf, NHERF-1, nherf-1, NHERF1, nherf1, NPHLOP2, SLC9A3R1, slc9a3r1, slc9a3r2, wu:fd20a02, zgc:55541, zgc:77629

Protein level used designations for SLC9A3R1

  • Na(+)/H(+) exchange regulatory cofactor NHE-RF1
  • Na+/H+ exchange regulatory co-factor
  • ezrin-radixin-moesin binding phosphoprotein-50
  • ezrin-radixin-moesin-binding phosphoprotein 50
  • regulatory cofactor of Na(+)/H(+) exchanger
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
  • solute carrier family 9 isoform A3 regulatory factor 1
  • EBP50
  • NHERF-1
  • sodium-hydrogen exchanger regulatory factor 1
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  • solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1
  • nherf1
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
  • ERM-binding phosphoprotein
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF
  • solute carrier family 9 isoform 3 regulatory factor 1
  • NHE3 kinase A regulatory protein 1
  • SLC9A3 regulator 1 S homeolog
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 S homeolog
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