SLC9A3R1 产品
(Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))
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This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009].
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Featured SLC9A3R1 Categories
SLC9A3R1 抗体
High quality antibodies with extensive validation data.
SLC9A3R1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLC9A3R1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA
Validations
- (4)
Cat. No.
ABIN522831
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN6265156
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (1)
- (3)
Cat. No.
ABIN652034
Quantity
400 μL
Datasheet
Datasheet
Recommended SLC9A3R1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320545
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320543
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2732190
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our SLC9A3R1 Products
: "Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. ..." in: The Journal of allergy and clinical immunology, Vol. 139, Issue 2, pp. 607-620.e15, (2016) (PubMed).: "EBP50 inhibits pancreatic cancer cell growth and invasion by targeting the β-catenin/E-cadherin pathway." in: Experimental and therapeutic medicine, Vol. 10, Issue 4, pp. 1311-1316, (2015) (PubMed).
: "Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease." in: The Journal of international medical research, Vol. 43, Issue 5, pp. 629-38, (2015) (PubMed).
: "NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16960-74, (2013) (PubMed).
: "Cell cycle dependent association of EBP50 with protein phosphatase 2A in endothelial cells." in: PLoS ONE, Vol. 7, Issue 4, pp. e35595, (2012) (PubMed).
: "Proprotein convertase 5/6 is critical for embryo implantation in women: regulating receptivity by cleaving EBP50, modulating ezrin binding, and membrane-cytoskeletal interactions." in: Endocrinology, Vol. 152, Issue 12, pp. 5041-52, (2011) (PubMed).
: "NHERF1 regulates parathyroid hormone receptor desensitization: interference with beta-arrestin binding." in: Molecular pharmacology, Vol. 75, Issue 5, pp. 1189-97, (2009) (PubMed).
: "NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands." in: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2527-37, (2007) (PubMed).
: "Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function." in: Oncogene, Vol. 26, Issue 36, pp. 5290-9, (2007) (PubMed).
: "NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors." in: The Journal of biological chemistry, Vol. 282, Issue 34, pp. 25076-87, (2007) (PubMed).
Synonyms and alternative names related to SLC9A3R1
SLC9A3 regulator 1 (SLC9A3R1), microRNA 3615 (MIR3615), solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a (slc9a3r1a), solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1), SLC9A3 regulator 1 (Slc9a3r1), SLC9A3 regulator 1 S homeolog (slc9a3r1.S), cb895, EBP-50, EBP50, NHE-RF, NHERF, nherf, NHERF-1, nherf-1, NHERF1, nherf1, NPHLOP2, SLC9A3R1, slc9a3r1, slc9a3r2, wu:fd20a02, zgc:55541, zgc:77629Protein level used designations for SLC9A3R1
- Na(+)/H(+) exchange regulatory cofactor NHE-RF1
- Na+/H+ exchange regulatory co-factor
- ezrin-radixin-moesin binding phosphoprotein-50
- ezrin-radixin-moesin-binding phosphoprotein 50
- regulatory cofactor of Na(+)/H(+) exchanger
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
- solute carrier family 9 isoform A3 regulatory factor 1
- EBP50
- NHERF-1
- sodium-hydrogen exchanger regulatory factor 1
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
- solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1
- nherf1
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
- ERM-binding phosphoprotein
- Na(+)/H(+) exchange regulatory cofactor NHE-RF
- solute carrier family 9 isoform 3 regulatory factor 1
- NHE3 kinase A regulatory protein 1
- SLC9A3 regulator 1 S homeolog
- solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 S homeolog
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